Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang +9 more
wiley +1 more source
Dumpling Suture Method Versus Traditional Suture Method of Diverting Loop Ileostomy in Laparoscopic Anterior Rectal Resection With Specimen Extraction Through Stoma Incision: A Randomized, Parallel-Controlled Trial. [PDF]
Liang Z +7 more
europepmc +1 more source
Osteology of the Hamadryas Baboon (Papio hamadryas). [PDF]
Casteleyn C, Wydooghe E, Bakker J.
europepmc +1 more source
Contributions towards a knowledge of the Curculionidae [PDF]
Pascoe, Francis Polkinghorne
core
Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang +8 more
wiley +1 more source
[Update on Meniscal Injury Treatment]. [PDF]
Paula RE, Alves BC, Mozella AP.
europepmc +1 more source
[Skeletal maturation of the hand and wrist and ossification of the mid palate suture in adolescents: a literature review]. [PDF]
Ramirez-Diaz RE, Watanabe Kanno GA.
europepmc +1 more source
Novel Vascular‐Adaptive Liquid Metal Microspheres Enable Visualized Arterial Embolization Therapy
We present drug‐loaded liquid metal microspheres (X‐MEN) as a novel agent for image‐guided arterial embolization. With inherent radiopacity and superior deformability, X‐MEN enables real‐time monitoring and conforms tightly to irregular vessels. This approach ensures precise, long‐lasting embolization without recanalization, addressing critical ...
Chenyu Shen +14 more
wiley +1 more source
Midpalatal suture split after differential and fan-type expansion: a secondary analysis from a randomized clinical trial. [PDF]
Garib D +5 more
europepmc +1 more source

