Results 201 to 210 of about 128,325 (262)

The Effect of Ecopipam on the Pharmacokinetics of Concomitant Medications

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Ecopipam is a first‐in‐class dopamine D1 receptor antagonist under investigation for the treatment of Tourette syndrome. This open‐label, fixed‐sequence, three‐cohort study evaluated whether ecopipam induces or inhibits cytochrome P450 (CYP) 1A2, CYP2B6, CYP2C19, CYP2D6, CYP3A4, organic anion‐transporting polypeptide (OATP) 1B1, and p ...
Virginia D. Schmith, Danielle Graden, Lauren L. R. Lohmer, Joy Schleyer, Stephen P. Wanaski   +4 more
wiley   +1 more source

A Multi-Stage Hybrid Learning Model with Advanced Feature Fusion for Enhanced Prostate Cancer Classification. [PDF]

Diagnostics (Basel)
Abd El-Ghany S, Abd El-Aziz AA.
europepmc   +1 more source

Findings on Magnetic Resonance Imaging in Neuroborreliosis—A Nationwide Cohort Study

European Journal of Neurology, Volume 33, Issue 2, February 2026.
Key MRI findings in neuroborreliosis include leptomeningeal, cranial nerve, and nerve root enhancement, often without corresponding symptoms. Spinal cord lesions were relatively frequent and white matter lesions were non‐specific and associated with increasing age.
Mathilde Ørbæk, Nitesh Shekhrajka, Rosa Maja Møhring Gynthersen, Jacob Bodilsen, Lykke Larsen, Merete Storgaard, Christian Brandt, Lothar Wiese, Birgitte Rønde Hansen, Hans R. Luttichau, Aase Bengaard Andersen, Helene Mens, Henrik Nielsen, Klaus Hansen, Anne‐Mette Lebech, The DASGIB Study Group   +15 more
wiley   +1 more source

Neighborhood deprivation and midlife cognition: Evidence of a modifiable vascular pathway involving health behaviors and cerebral small vessel disease. [PDF]

Alzheimers Dement
Low A, Tsvetanov KA, Ntailianis G, Prats-Sedano MA, McKiernan E, Carter SF, Stefaniak JD, Nannoni S, Su L, McKeever A, Dounavi ME, Muniz-Terrera G, Bridgeman K, Gregory S, Ritchie K, Lawlor B, Naci L, Connolly C, Malhotra P, Koychev I, Ritchie CW, O'Brien JT, PREVENT Dementia Investigators.   +22 more
europepmc   +1 more source

Alveolar deadspace and intrapulmonary shunt in healthy individuals and in individuals who have recovered from COVID‐19 infection

Experimental Physiology, Volume 111, Issue 2, Page 556-567, 1 February 2026.
Abstract Following acute COVID‐19 infection, unvaccinated patients have been reported to exhibit elevated alveolar deadspace (̇VD,alv/̇VT) and intrapulmonary shunt (̇Qs/̇QT) fractions. However, as there is uncertainty surrounding the upper limits of normal for ̇VD,alv/̇VT and ̇Qs/̇QT, we sought to replicate the findings from a separate, previously ...
Dominic Sandhu, Snapper R. M. Magor‐Elliott, Nayia Petousi, Nick P. Talbot, Alexander N. Bennett, David A. Holdsworth, Grant A. D. Ritchie, Peter A. Robbins   +7 more
wiley   +1 more source

Two-conformer equilibrium of maltose-binding protein in the absence of ligand from residual dipolar coupling analysis. [PDF]

Protein Sci
Shen Y, Bax A.
europepmc   +1 more source

Editorial: Moves towards SVD eradication

Veterinary Record, 1975
openaire   +2 more sources

The effect of sex on the isolated and combined α‐ and β‐adrenergic control of blood flow during handgrip in adults at high altitude: An exploratory study

Physiological Reports, Volume 14, Issue 3, February 2026.
Abstract This study examined how sex influences blood flow during exercise at altitude and relative contributions of adrenergic mechanisms. Thirteen participants (8 M/5F) were tested at low and high altitude (days 3–11). Participants performed rhythmic handgrip for 3 min at 25% maximal voluntary contraction during local infusions of saline, propranolol
Lauren E. Maier, Emily R. Vanden Berg, Lydia Simpson, Michiel Ewalts, Katharine Foster, Jared Baylis, Christopher Gasho, David Macleod, Sean van Diepen, James Anholm, Justin Lawley, Philip N. Ainslie, Travis D. Gibbons, Michael Stembridge, Jonathan Moore, Craig D. Steinback   +15 more
wiley   +1 more source

Investigating the Sudan virus outbreak in Uganda through the deployment of a mobile laboratory. [PDF]

BMC Infect Dis
Pimundu G, Muyigi T, Nambozo EJ, Okiira C, Kanamwanji B, Nalwanga R, Sekate J, Mugabe R, Naiga J, Sewanyana I, Lutwama J, Balinandi S, Kaleebu P, Aceng JR, Atwiine D, Mwebesa H, Bosa HK, Kagirita A, Olaro C, Nsawotebba A, Achol E, Lagu H, Nzeyimana E, May J, Gehre F, Affara M, Nabadda S.   +26 more
europepmc   +1 more source

Non‐Linear Reduced Order Modelling of Transonic Potential Flows for Fast Aerodynamic Analysis

International Journal for Numerical Methods in Engineering, Volume 127, Issue 2, 30 January 2026.
ABSTRACT This work presents a physics‐based reduced order modelling (ROM) framework for the efficient simulation of steady transonic potential flows around aerodynamic configurations. The approach leverages proper orthogonal decomposition and a least‐squares Petrov‐Galerkin (LSPG) projection to construct intrusive ROMs for the full potential equation ...
M. Zuñiga, S. Ares de Parga, R. Zorrilla, R. Rossi   +3 more
wiley   +1 more source