Results 221 to 230 of about 61,045 (270)

Real‐World Effectiveness and Safety of Sofosbuvir‐Based Therapy in Chinese Children and Adolescents With Chronic HCV Infection: A Retrospective Multicentre Study

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 12, December 2026.
ABSTRACT Few direct‐acting antiviral regimens are approved in China for children and adolescents with chronic hepatitis C virus (HCV) infection and data are limited on their efficacy and safety in this population. This retrospective, multi‐centre study aimed to assess the real‐world effectiveness and safety of ledipasvir/sofosbuvir (LDV/SOF) and ...
Li Liu   +12 more
wiley   +1 more source

Clinical Characteristics of Coccidioidomycosis in Patients with Hepatitis C-Associated Cirrhosis. [PDF]

open access: yesMicroorganisms
Shepard R   +4 more
europepmc   +1 more source

Direct Comparison Between Loss‐to‐Follow‐Up and Statistical Fragility Is Methodologically Inappropriate, and Fragility Reflects the P Value, Not Trial Robustness: A Simulation Analysis of 300,000 Randomized Controlled Trials

open access: yesArthroscopy, Volume 42, Issue 11, Page 2749-2758, November 2026.
Purpose To assess the relation between the fragility index (FI) and reverse fragility index (RFI) with the minimum number of patients needed to reverse statistical significance (e.g. henceforth termed the lost to follow‐up index (LTFI) and reverse LTFI (R‐LTFI), respectively) and apply machine learning to identify which trial parameters are most ...
Prushoth Vivekanantha   +7 more
wiley   +1 more source

Machine Learning‐Based PAT Tool for Real‐Time Residual Moisture Monitoring in Lyophilized Biopharmaceuticals Using NIR Spectroscopy

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 11, Page 3030-3046, November 2026.
ABSTRACT There is a growing demand in the pharmaceutical industry to optimize analytical methodologies, reducing time and resource consumption while ensuring rapid process development and cost‐efficient manufacturing. Indeed, Food and Drug Administration (FDA) introduced the Process Analytical Technology (PAT) as an initiative enabling manufacturers to
Samuele Fiorenza   +5 more
wiley   +1 more source

Carbon‐Based Adsorbents for CO2 Capture: Mechanism‐Guided Material Design and Data‐Driven Optimization

open access: yesCarbon Neutralization, Volume 5, Issue 6, November 2026.
The main purpose of this review is to summarize recent progress in the broad family of carbon‐based materials and their derivatives for CO2 capture. Rather than focusing on a single precursor or modification route, it examines pristine carbon adsorbents, functionalized carbon derivatives, and carbon‐based composites within a unified framework.
Jinliang Cai   +4 more
wiley   +1 more source

Development of a Machine Learning Model to Predict Short Duration HCV Treatment Response. [PDF]

open access: yesJ Viral Hepat
Carson JM   +7 more
europepmc   +1 more source

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