Results 41 to 50 of about 137,721 (313)

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

A profile of a paediatric population with feeding and swallowing difficulties at a tertiary hospital in the Western Cape [PDF]

, 2012
Includes abstract.Includes bibliographical resources.Feeding and/or swallowing difficulties (FSD) have been associated with some of the leading causes of infant and child mortality in South Africa.
Oosthuizen, Nicolene
core  

Swallowing activity assessed by ambulatory impedance-pH monitoring predicts awake and asleep periods at night. [PDF]

, 2013
INTRODUCTION: Voluntary muscle activity, including swallowing, decreases during the night. The association between nocturnal awakenings and swallowing activity is under-researched with limited information on the frequency of swallows during awake and ...
Arevalo, F, Pohl, D., Freeman, J., Arevalo, F., Singh, E, Tutuian, Radu, Pohl, D, Freeman, J, Singh, E., Castell, D. O., Tutuian, R, Castell, D O   +11 more
core   +1 more source

Techniques of restoring swallowing mechanisms in the treatment of patients with head and neck cancer: postoperative pain relief, plastic surgery and diet

Russian Open Medical Journal, 2020
Objective — to review available publications and identify unresolved issues in assessing the functional state of the oral cavity and pharynx, along with swallowing disorders in oncopathology of head and neck, depending on the treatment method.
Anna А. Kushta, Sergey М. Shuvalov
doaj   +1 more source

Hierarchical Multi‐Material Architectures With Gradient Design for Dynamic‐Range Flexible Tactile Sensing

Advanced Materials Technologies, EarlyView.
Hierarchical multi‐material TPMS lattices are engineered as flexible tactile sensors by combining soft and stiff elastomeric layers with a conformal conductive coating. The bilayer architecture delivers sensitivity at low pressures while maintaining a broad detectable range under large loads, enabling reliable pressure and vibration monitoring for ...
Reza Noroozi, Domenic Quiquero, Yan Yan Shery Huang, HaoTian Harvey Shi   +3 more
wiley   +1 more source

The Effect of Bolus Consistency and Age on Measurements of Hyolaryngeal Muscular Activity During Swallowing [PDF]

, 2014
The objective of this study was to measure the effect of Age and Bolus Consistency on Hyolaryngeal Muscular Activity in older healthy adult males (ages 60-90) as compared to younger healthy males (ages 18-25) using Surface Electromyography (sEMG).
Post, Danielle
core  

Longitudinal change in swallow function in patients with Parkinson's disease (PD)

Journal of Parkinson’s Disease
Objective Parkinson's disease (PD) frequently involves dysphagia, yet real-world longitudinal data capturing its progression and response to clinical care remain limited.
Camryn R Marshall, VyVy N Young, Zoe Weston, Sarah L Schneider, Tyler W Crosby, Clark A Rosen, Steve D Stockton, Ian O Bledsoe, Yue Ma   +8 more
doaj   +1 more source

Ultrasound examination of swallowing disorder characteristics in patients with oncopathology of the oral cavity

Zaporožskij Medicinskij Žurnal, 2021
The aim of the study was to compare the dynamics of oral and oropharyngeal muscles contraction during swallowing in normal individuals and in patients with malignant tumors depending on the clinical disease using ultrasound. Materials and methods. The
A. O. Kushta
doaj   +1 more source

SWALLOWING A WHISTLE. [PDF]

The Lancet
n ...
openaire   +2 more sources

Flexible Pressure Sensor With Co‐Optimized Sensitivity and Linearity Based on Gradient Toroidal Microstructures

Advanced Materials Technologies, EarlyView.
A flexible piezoresistive pressure sensor with gradient toroidal CNT/PDMS microstructures is reported. The hierarchical geometry enables sequential electrode contact, achieving a sensitivity of 256.20 kPa−1 and linear response (R2 = 0.99) over 0–1000 kPa.
Rongmei Wang, Ruolin Liu, Ming Lei, Yifan Liu, Fengming Hu, Bing Ji, Chao Peng, Jianyi Luo, Bingpu Zhou   +8 more
wiley   +1 more source