Results 91 to 100 of about 2,227 (290)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

A theoretical and practical analysis of the optimum breeding system for perennial ryegrass [PDF]

open access: yes, 2011
peer-reviewedThe goal of plant breeding is to effectively and efficiently select for the best phenotypes leading to the development of improved cultivars. The objectives for this review are to describe and critically evaluate breeding methods appropriate
Conaghan, Patrick, Casler, M.D.
core  

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

open access: yesAdvanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu   +11 more
wiley   +1 more source

Meralarda Farklı Otlatma Yoğunluklarının Bastırılmış Ot Katı Yüksekliği ve Ak Üçgülün Trifolium repens L. Görülme Sıklığına Etkisi

open access: yesJournal of Agricultural Sciences, 2008
Amaç, devamlı otlatılan meralarda, orta-yoğun ve hafif otlatmada bastırılmış ot katı yükseklik gruplarının dağılımı ve bu yükseklik grupları içerisinde ak üçgülün T.repens görülme sıklığını 4 farklı gözlem döneminde karşılaştırmaktır.
Nurdan Şahin Demirbağ
doaj   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

open access: yesAdvanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo   +5 more
wiley   +1 more source

Responses in Ingestive Behavior by Sheep Changes in Sward Structure [PDF]

open access: yes
Recent work has shown how herbage growth, ingestive behaviour and herbage intake may be related to sward height under continuous stocking (Parsons et al., 1986; Penning, 1986). However, the application of these relationships to other grazing managements,
Hooper, G E   +3 more
core  

Caracterização da estrutura da vegetação numa pastagem natural do Bioma Pampa submetida a diferentes estratégias de manejo da oferta de forragem Structural characterization of a natural pasture vegetation from Pampa Biome under different herbage allowance management strategies

open access: yesRevista Brasileira de Zootecnia, 2009
Os objetivos neste trabalho foram descrever e investigar a dinâmica espaço-temporal de sítios alimentares em diferentes faixas de massa de forragem e altura do pasto, assim como o percentual de área efetivamente pastejada, a taxa de acúmulo de forragem e
Fabio Pereira Neves   +5 more
doaj   +1 more source

Engineered Au@CeO2 Hybrid Nanoparticles With Microenvironment Dependent Self‐Adjustability for Integration of Tumor‐Specific Photothermal‐Chemodynamic Therapy and Inflammation Prevention

open access: yesAdvanced Science, EarlyView.
An intelligent Au@CeO2 Hybrid Nanoparticles (ACEF) with microenvironment‐dependent self‐adjustability was engineered to not only perform efficient and tumor‐specific photothermal‐chemodynamic therapy for precise tumor elimination, but also serve as a ROS scavenger in healthy tissues around the tumor to avoid the unexpected oxidative damage and ...
Wenyun Mu   +8 more
wiley   +1 more source

Requirements of future grass-based ruminant production systems in Ireland [PDF]

open access: yes, 2011
peer-reviewedThere is a renewed interest in grazing systems in many temperate and subtropical regions of the world. This results from lower inflation-adjusted prices, the proposed removal of some subsidies and tariffs, and rising labour, machinery and ...
O'Donovan, Michael   +2 more
core  

Interaction among fire and sward height increases leaf nitrogen per unit area of annual ryegrass in subtropical grasslands from southern Brazil [PDF]

open access: yesCiência Rural
: Fire is one of the main drivers of vegetation structure from terrestrial ecosystems and its effects on plants allocation resources and biomass are mediated by leaf functional traits. These attributes can provide useful information for future management
Fernando Forster Furquim   +3 more
doaj   +1 more source

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