Results 81 to 90 of about 7,174,007 (240)

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Sward botanical composition and sward quality affect the foraging behaviour of free-range laying hens

, 2014
In a two-year experiment, we investigated the influence of sward plant species composition (sward type), stocking duration and state of sward degradation on the foraging behaviour of chickens.
Breitsameter, Laura, Gauly, Matthias, Laura Breitsameter, Matthias Gauly, Isselstein, Johannes, Johannes Isselstein   +5 more
core   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Optimising sward structure and herbage yield for the performance of dairy cows at pasture. [PDF]

, 1999
End of Project ReportsThe basic unit of intake is the bite. The total daily intake of grazed grass is determined by the number of bites taken and the weight of the average bite.
Brereton, A. J., Casey, Imelda A.
core   +1 more source

Dual‐Targeted Biomimetic MoSe2 Nanozymes for Enhancing Peri‐Implant Soft Tissue Integration

Advanced Science, EarlyView.
A dual‐targeting biomimetic nanozyme, MoSe2@SPMM, selectively targets Staphylococcus aureus and oxidatively stressed macrophages. Near‐infrared activation couples contact‐enhanced photothermal bacterial eradication with reactive oxygen species scavenging to disrupt the pathogenic–immunological amplification loop.
Minghao Zhou, Miaomiao Tian, Jingwei Yu, Jiaxin Kang, Miaomiao Chen, Yue Yuan, Lizhi Liu, Hongbo Wei   +7 more
wiley   +1 more source

Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice

Advanced Science, EarlyView.
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang, Bo Liu, Can Hu, Chenfan Zheng, Yuting Wei, Xier Xu, Wei Yang, Yu Fang, Guangle Shen, Pedro García‐Caparros, Conghe Zhang, Qingyao Shu, Meng Jiang   +12 more
wiley   +1 more source

Relações planta-animal em ambiente pastoril heterogêneo: padrões de desfolhação e seleção de dietas Plant-animal relationships in pastoral heterogeneous environments: defoliation and selectivity patterns

Revista Brasileira de Zootecnia, 2009
Um experimento foi conduzido para avaliar o efeito das alturas de manejo do pasto (4, 8, 12 e 16 cm) no padrão de desfolhação de uma pastagem nativa e na seletividade de bezerras e ovelhas em testes de pastejo de 45 minutos.
Edna Nunes Gonçalves, Paulo César de Faccio Carvalho, Carlos Eduardo Gonçalves da Silva, Davi Teixeira dos Santos, José Augusto Queirolo Díaz, Carolina Baggio, Carlos Nabinger   +6 more
doaj   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

Relações planta-animal em ambiente pastoril heterogêneo: padrões de deslocamento e uso de estações alimentares Plant-animal relationships in a heterogeneous pastoral environment: displacement patterns and feeding station use

Revista Brasileira de Zootecnia, 2009
Avaliou-se como o padrão de deslocamento e de utilização de estações alimentares podem ser afetados por alturas de manejo de 4, 8, 12 e 16 cm numa pastagem nativa.
Edna Nunes Gonçalves, Paulo César de Faccio Carvalho, Thais Devincenzi, Marília Lazzarotto Terra Lopes, Fabiana Kellermann de Freitas, Aino Victor Ávila Jacques   +5 more
doaj   +1 more source

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

Advanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai, Jikuang Zhao, Chang Xue, Kailei Xu, Liang Yong, Zhuangwei Zhang, Yi Huang, Jianwei Shuai, Xianzhen Chen, Sheng Nie, Junpeng Xu   +10 more
wiley   +1 more source