Results 41 to 50 of about 17,374 (255)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Swarm Intelligence-Based Performance Optimization for Mobile Wireless Sensor Networks: Survey, Challenges, and Future Directions

IEEE Access, 2019
Network performance optimization has always been one of the important research subjects in mobile wireless sensor networks. With the expansion of the application field of MWSNs and the complexity of the working environment, traditional network ...
Li Cao, Yong Cai, Yinggao Yue
doaj   +1 more source

Performance Modeling of Load Balancing Techniques in Cloud: Some of the Recent Competitive Swarm Artificial Intelligence-based

Journal of Intelligent Systems, 2020
Cloud computing deals with voluminous heterogeneous data, and there is a need to effectively distribute the load across clusters of nodes to achieve optimal performance in terms of resource usage, throughput, response time, reliability, fault tolerance ...
Bhargavi K, Sathish Babu B, Pitt Jeremy
doaj   +1 more source

Convergence Analysis and Performance Comparison of Cuckoo Search Algorithm

Jisuanji kexue yu tansuo, 2020
Swarm intelligence algorithm is an emerging optimization method, which connects simple individuals through teamwork and organization to generate swarm intelligence and is used to solve practical problems.
LIU Xiaodong, SUN Lijun, CHEN Tianfei
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Localization and tracking of multiple quadrotors with collision avoidance: Theory and experiment

Defence Technology
Multiple quadrotors target encirclement is widely used in the intelligent field, as it can effectively monitor and control target behavior. However, it faces the danger of collision, as well as difficulties in localization and tracking.
Guang Yang, Juntong Qi, Mingming Wang, Yan Peng, Chong Wu, Yuan Ping, Hailong Huang   +6 more
doaj   +1 more source

Simulation Study of Swarm Intelligence Based on Life Evolution Behavior

Discrete Dynamics in Nature and Society, 2015
Swarm intelligence (SI) is a new evolutionary computation technology, and its performance efficacy is usually affected by each individual behavior in the swarm.
Yanmin Liu, Ying Bi, Changling Sui, Yuanfeng Luo, Zhuanzhou Zhang, Rui Liu   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source