Results 51 to 60 of about 610,219 (332)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Human eccrine sweat gland cells can reconstitute a stratified epidermis [PDF]

, 2010
Eccrine sweat glands are generally considered to be a possible epidermal stem cell source. Here we compared the multilayered epithelia formed by epidermal keratinocytes and those formed by eccrine sweat gland cells.
Braziulis, E, Tharakan, Sasha, Pontiggia, L; https://orcid.org/, Reichmann, E, Schiestl, C, Schiestl, Clemens, Braziulis, Erik, Böttcher-Haberzeth, S, Meuli, M, Pontiggia, Luca, Tharakan, S, Böttcher-Haberzeth, Sophie, Meuli, Martin, Biedermann, T, Biedermann, Thomas, Reichmann, Ernst   +15 more
core   +1 more source

Sweat gland adenocarcinoma of scalp

International Journal of Trichology, 2013
Sweat gland adenocarcinoma is a rare tumor particularly over scalp. They have potential to be benign as well as distant metastasis. Usually presents with papules or nodules. Ulcerative morphology is uncommon. Wide surigical excision with regional lymph not dissection is the treatment of choice.
Nair, Pragya A, Rathod, Kirti M, Chaudhary, Arvind H, Pilani, Abhishek P   +3 more
openaire   +3 more sources

Mammaglobin in Normal Human Sweat Glands and Human Sweat Gland Tumors [PDF]

Journal of Investigative Dermatology, 2003
Secretoglobins is a newly described polypeptide family that has gained a lot of interest in human cancer and inflammation research. Although the first secretoglobin polypeptide was discovered more than 30 years ago, their physiological function is still not known.
Sjödin, Anna, Guo, Dongsheng, Henriksson, Roger, Hedman, Håkan, Hofer, Per-Åke   +4 more
openaire   +2 more sources

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

A deep learning strategy to estimate the sweat rate per gland from digital sweat sensing

Discover Sensors
Sweat sensing technology may enable continuous non-invasive patient monitoring. However, the clinical interpretation of biomarker concentrations in sweat may be hampered by their dependence on the sweat rate per gland.
Jelte R. Haakma, Simona Turco, Esmee Esselaar, Massimo Mischi, Elisabetta Peri   +4 more
doaj   +1 more source

Gap junction-mediated contraction of myoepithelial cells induces the peristaltic transport of sweat in human eccrine glands

Communications Biology, 2023
Eccrine sweat glands play an essential role in regulating body temperature. Sweat is produced in the coiled secretory portion of the gland, which is surrounded by obliquely aligned myoepithelial cells; the sweat is then peristaltically transported to the
Kie Nakashima, Hiroko Kato, Ryuichiro Kurata, Luo Qianwen, Tomohisa Hayakawa, Fumihiro Okada, Fumitaka Fujita, Yukinobu Nakagawa, Atsushi Tanemura, Hiroyuki Murota, Ichiro Katayama, Kiyotoshi Sekiguchi   +11 more
doaj   +1 more source

Comparison of outcomes of two methods of axillary osmidrosis surgery: Subdermal excision versus liposuction combined with diode laser ablation [PDF]

Archives of Aesthetic Plastic Surgery, 2020
Background Patients with axillary osmidrosis suffer from a foul odor due to the bacterial decomposition of apocrine gland secretions. This condition is stressful, especially for teenaged students and young working people in Korea, who seek a reliable ...
Sung Won Jung, Seung Je Lee, Hye-Rim Park   +2 more
doaj   +1 more source