Results 71 to 80 of about 4,278 (233)

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Peptide‐based responsive molecular fluorescent probes for precision oncology

Responsive Materials, EarlyView.
Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang, Wen Liu, Jiahao Zhang, Wanqi Wang, Zhicheng Jin, Yuqi Tang, Quan Li   +6 more
wiley   +1 more source

Low-grade Hidradenocarcinomas: A Clinicopathologic Study of an Unusual Carcinoma That Can Mimic its Benign Counterpart.

, 2023
20.500.12530/87857Hidradenocarcinomas are rare cutaneous adnexal malignancies with sweat gland differentiation that can show a broad spectrum of histomorphologic appearances, ranging from low to high grade.
Roman, Jorge, Plaza, Jose A, Gru, Alejandro A, Davey, Jonathan, Sangueza, J Martin, Wakely, Paul, Brenn, Thomas   +6 more
core   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Creation, implementation and objectives of CARADERM, a national network for rare skin carcinomas - Adnexal neoplasm part

, 2019
International audienceIntroduction. - CARADERM is a French national network that includes patients with rare skin adnexal neoplasms. The present paper describes only the adnexal neoplasm part of this network.
d'Incan, M., Lebbe, C., Leccia, M. T., Ortonne, N., Zehou, O., Lorton, Aubriot M. H., Grange, F., Algros, M. P., Machet, M., Derancourt, C., Granel-Brocard, F., Grob, J. J., Courville, P., Wierzbicka-Hainaut, E., Bens, G., Josselin, N., Beylot-Barry, M., Battistella, M., Fouchardiere, A., de La, Brunet-Possenti, F., Machet, L., Lemasson, G., Dalac, S., Carlotti, A., Guillot, B., Meyer, N., Verneuil, L., Dreno, B., Chatelain, Denis, Durand, L., Durlach, A., Arnault, J. P., Misery, L., Lamant, L., Macagno, N., Seris, A., Frouin, E., Dermatologie, Soc Francaise, Salle, Martin E., de La, Jouary, T., Dalle, S., Le Corre, Y., Robert, C., Lipsker, D., Balme, B., Blom, A., de Quatrebarbes, J., Lacour, J. P., Franck, F., Mortier, L., Maubec, E., Bedane, C., Neidhart-Berard, E-M, Dupuy, A., Aubin, F., Maillard, H., Joly, P., Cribier, B., Jullie, M-L, Zimmermann, U., Kramkimel, N.   +60 more
core   +1 more source

Basal Cell Carcinoma and Syringocystoadenoma Papilliferum Arising in Naevus Sebaceous—A Narrative Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Naevus sebaceous (NS) is a congenital cutaneous hamartoma characterised by epidermal, follicular, sebaceous and apocrine components, with a rare but significant potential for malignant transformation, most commonly into basal cell carcinoma (BCC).
Yajat Dua, Chris Miller, Anand Ramakrishnan   +2 more
wiley   +1 more source

Ultrasonographic Features of Spiradenomas and Cylindromas as Diagnostic Clues in the Pre‐Therapeutic Setting

JEADV Clinical Practice, EarlyView.
Diana Crisan, Tina Weiss, Karin Scharffetter‐Kochanek, Yusef Sallum, Ioana‐Ancuta Ungureanu, Maria Crisan   +5 more
wiley   +1 more source