Results 81 to 90 of about 4,278 (233)

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Skin adnexal tumors unveiled: A tertiary care perspective from North India

Asian Journal of Medical Sciences
Background: Skin adnexal tumors (SATs) encompass wide spectrum of benign and malignant tumors that differentiate toward one or more adnexal structures found in normal skin.
Richa Pawar , Pooja Rathee , Sunita Singh , Sumiti Gupta , Meenu Gill , Sonia Chabbra , Monika Gupta, Promil Jain , Usha Rani   +8 more
doaj   +1 more source

Enlarging Fingertip Nodule Mimicking a Pyogenic Granuloma in a Man in his 60's

JEADV Clinical Practice, EarlyView.
Avery H. Seward, Jocelyn H. LaRocque, Stephen M. Hughes   +2 more
wiley   +1 more source

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Gross cystic disease fluid protein-15 in salivary gland tumors.

, 1991
Gross cystic disease fluid protein-15 (GCDFP-15) is a 15-kd glycoprotein that is expressed by normal apocrine epithelia and in a majority of breast carcinomas. However, recent studies have demonstrated that this substance is also present in tumors of the
T. J. Lillemoe, PETTINATO, GUIDO, P. E. Swanson, M. R. Wick   +3 more
core  

Multicentric Asynchronous Endocrine Mucin‐Producing Sweat Gland Carcinoma and Mucinous Carcinoma of the Skin

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Endocrine mucin‐producing sweat gland carcinoma (EMPSGC) is an adnexal neoplasm which typically occurs on periorbital skin and demonstrates overlapping histopathologic features with primary mucinous carcinoma of the skin (MCS). Herein, we report a patient who developed five distinct lesions of EMPSGC and MCS over an eight‐year period, some of ...
Ikuko Hirai, Joseph F. Sobanko, Tara C. Mitchell, Jacquelyn Roth, Rosalie Elenitsas, Emily Y. Chu   +5 more
wiley   +1 more source

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil, Hozaifa Elameen, Ahmed K. Alomari   +2 more
wiley   +1 more source

Immunohistochimie des tumeurs mésenchymateuses cutanées à cellules fusiformes du chat (complexe du fibrosarcome félin) : études préliminaires de marqueurs de différenciation [PDF]

, 2001
Les sarcomes cutanés félins à cellules fusiformes (SCF) représentent 12 à 41 % des tumeurs cutanées et leur incidence est à la hausse depuis quelques années.
Herbet, Aurélia
core  

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann, Ulrike Wieland, Steffi Silling, Frank Oellig, David Chromy, Julia Hyun, Thilo Gambichler, Alexander Kreuter   +7 more
wiley   +1 more source

Gene fusions in poroma, porocarcinoma and related adnexal skin tumours: An update

International audiencePoroma is a benign sweat gland tumour showing morphological features recapitulating the superficial portion of the eccrine sweat coil. A subset of poromas may transform into porocarcinoma, its malignant counterpart.
Hamard, Aymeric, Barlier, Anne, Kervarrec, Thibault, Macagno, Nicolas, Sohier, Pierre, Pissaloux, Daniel, Tirode, Franck, Fouchardiere, Arnaud, de La, Battistella, Maxime, Cribier, Bernard, Frouin, Eric, Schrama, David, Houben, Roland   +12 more
core   +1 more source