Results 41 to 50 of about 548,390 (342)

In Vivo Readout of CFTR Function: Ratiometric Measurement of CFTR-Dependent Secretion by Individual, Identifiable Human Sweat Glands

PLoS ONE, 2013
To assess CFTR function in vivo, we developed a bioassay that monitors and compares CFTR-dependent and CFTR-independent sweat secretion in parallel for multiple (∼50) individual, identified glands in each subject. Sweating was stimulated by intradermally
J. Wine, Jessica E. Char, Jonathan H. Chen, Hyung-Ju Cho, C. Dunn, E. Frisbee, N. Joo, C. Milla, Sara E. Modlin, I. Park, Ewart A. C. Thomas, Kim V. Tran, Rohan Verma, Marlene H. Wolfe   +13 more
semanticscholar   +1 more source

Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay, E. Vichayanrat, F. Bremner, F. Valerio, R. Mackenzie, G. Chiaro, G. Ingle, P. McNamara, L. Watson, J. N. Panicker, M. P. Lunn, C. Mathias, V. Iodice   +12 more
wiley   +1 more source

Eccrine sweat gland development and sweat secretion [PDF]

Experimental Dermatology, 2015
AbstractEccrine sweat glands help to maintain homoeostasis, primarily by stabilizing body temperature. Derived from embryonic ectoderm, millions of eccrine glands are distributed across human skin and secrete litres of sweat per day. Their easy accessibility has facilitated the start of analyses of their development and function.
Chang-Yi Cui, David Schlessinger
openaire   +3 more sources

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang, Kang‐Yang Jih, Cheng‐Tsung Hsiao, Fu‐Pang Chang, Justus Chunyu Chen, Yi‐Chu Liao, Yih‐Ru Wu, Yi‐Chung Lee   +7 more
wiley   +1 more source

Physiology of sweat gland function: The roles of sweating and sweat composition in human health

Temperature, 2019
The purpose of this comprehensive review is to: 1) review the physiology of sweat gland function and mechanisms determining the amount and composition of sweat excreted onto the skin surface; 2) provide an overview of the well-established ...
Lindsay B. Baker
semanticscholar   +1 more source

Key Trends and Insights in Smart Polymeric Skin Wearable Patches

Advanced Engineering Materials, EarlyView.
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez, Rajat Rai, Miryam Criado‐Gonzalez   +2 more
wiley   +1 more source

Advanced Cellulose‐Based Gels for Wearable Physiological Monitoring: From Fiber Modification to Application Optimization

Advanced Functional Materials, EarlyView.
This review discusses cellulose‐based hydrogels technology, analyzes their application progress in physiological signal monitoring, and explores the effects of pretreatment, crosslinking, and molding methods on gel performance, to provide valuable insights into the efficient utilization of plant fibers and the environmentally friendly development of ...
Zhiming Wang, Jinxuan Jiang, Kexin Wei, Xiaojian Zhou, Muhammad Wakil Shahzad, Yifan Li, Xuehua Zhang, Ben Bin Xu, Shengbo Ge   +8 more
wiley   +1 more source

Effects of age on histological parameters of the sweat glands of Nellore cattle

Revista Ceres, 2015
The sweat glands are important in thermoregulation of cattle in a warm environment as they help dissipate heat through evaporation. Studies on gland histology are important to define its secretion potential and the capacity of perspiration and heat ...
Mara Regina Bueno de Mattos Nascimento, Enéias Aurélio Dias, Thaisa Reis dos Santos, Gustavo Ferreira Ayres, Carolina Cardoso Nagib Nascimento, Marcelo Emílio Beletti   +5 more
doaj   +1 more source

Characterization of nucleic acids from extracellular vesicle-enriched human sweat

BMC Genomics, 2021
Background The human sweat is a mixture of secretions from three types of glands: eccrine, apocrine, and sebaceous. Eccrine glands open directly on the skin surface and produce high amounts of water-based fluid in response to heat, emotion, and physical ...
Geneviève Bart, Daniel Fischer, Anatoliy Samoylenko, Artem Zhyvolozhnyi, Pavlo Stehantsev, Ilkka Miinalainen, Mika Kaakinen, Tuomas Nurmi, Prateek Singh, Susanna Kosamo, Lauri Rannaste, Sirja Viitala, Jussi Hiltunen, Seppo J Vainio   +13 more
doaj   +1 more source

Ectodermal dysplasias: New perspectives on the treatment of so far immedicable genetic disorders

Frontiers in Genetics, 2022
The past decade has witnessed an expansion of molecular approaches facilitating the differential diagnosis of ectodermal dysplasias, a group of genetic diseases characterized by the lack or malformation of hair, teeth, nails, and certain eccrine glands ...
Holm Schneider
doaj   +1 more source