Results 61 to 70 of about 548,390 (342)

Targeting ectodysplasin promotor by CRISPR/dCas9-effector effectively induces the reprogramming of human bone marrow-derived mesenchymal stem cells into sweat gland-like cells

open access: yesStem Cell Research & Therapy, 2018
Background Patients with a deep burn injury are characterized by losing the function of perspiration and being unable to regenerate the sweat glands. Because of their easy accession, multipotency, and lower immunogenicity, bone marrow-derived mesenchymal
Sujing Sun   +6 more
doaj   +1 more source

Eccrine sweat gland carcinoma

open access: yesBrazilian Journal of Otorhinolaryngology, 2007
INTRODUCTIONThe differential diagnosis among the most frequent skin tumors, base-cell carcinoma and squamous-cell carcinoma, and the rare types, the sweat gland carci-nomas, is fundamental for the early diag-nosis and prognosis of a patient. These are classified as eccrine and apocrine, and the eccrine is the most common type.
Alessandra Zanoni   +6 more
openaire   +3 more sources

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Effects of the bovine SLICK1 mutation in PRLR on sweat gland area, FOXA1 abundance, and global gene expression in skin

open access: yesJournal of Dairy Science, 2022
: The SLICK1 mutation in the prolactin receptor (PRLR) results in a short-hair coat and increased ability to regulate body temperature during heat stress. It is unclear whether the mutation affects capacity for sweating.
F. Sosa   +11 more
doaj  

A novel organotypic 3D sweat gland model with physiological functionality.

open access: yesPLoS ONE, 2017
Dysregulated human eccrine sweat glands can negatively impact the quality-of-life of people suffering from disorders like hyperhidrosis. Inability of sweating can even result in serious health effects in humans affected by anhidrosis.
Patricia Klaka   +7 more
doaj   +1 more source

Eccrine poroma and porocarcinoma on the same unusual location: report on two cases [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
Eccrine poroma is a benign adnexal tumour of the uppermost portion of the intraepidermal eccrine sweat gland duct and acrosyringium. Eccrine porocarcinoma is the malignant phenotype arising from the intraepidermal portion of the eccrine sweat gland duct ...
Han Ma   +4 more
doaj   +2 more sources

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

open access: yesAdvanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz   +2 more
wiley   +1 more source

Sweat gland adenocarcinoma of scalp

open access: yesInternational Journal of Trichology, 2013
Sweat gland adenocarcinoma is a rare tumor particularly over scalp. They have potential to be benign as well as distant metastasis. Usually presents with papules or nodules. Ulcerative morphology is uncommon. Wide surigical excision with regional lymph not dissection is the treatment of choice.
Abhishek P Pilani   +3 more
openaire   +3 more sources

Human Skin Models in Biophotonics: Materials, Methods, and Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses how the optical properties of human skin can be replicated in human skin models. It describes the principles, materials, and techniques used to develop artificial skin for biophotonics research. Finally, the article highlights recent advances and shows how these models improve the study of light‐skin interactions without the need ...
Dardan Bajrami   +4 more
wiley   +1 more source

Gross cystic disease fluid protein 15 in stratum corneum is a potential marker of decreased eccrine sweating for atopic dermatitis.

open access: yesPLoS ONE, 2015
It is well known that eccrine sweating is attenuated in patients with atopic dermatitis (AD). We have reported by using proteome analysis that gross cystic disease fluid protein 15 (GCDFP15), a substance secreted from eccrine sweat glands, is decreased ...
Koji Kamiya   +7 more
doaj   +1 more source

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