Results 51 to 60 of about 285,460 (266)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Norsk Lingvistisk Tidsskrift, 2017 In Swedish today, du (‘you’) is sometimes used with generic reference. This use of generic du is often claimed to be a new invention, triggered by English influence in the late 20th century. However, in this article an analysis of occurrences of du from
Sanna Skärlund
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Lidar Measurements Supporting the Ocular Hazard Distance Calculation Using Atmospheric Attenuation
EPJ Web of Conferences, 2016 A series of lidar measurements has been performed at the Vidsel Test Range, Vidsel, situated in the inland of the very northern part of Sweden, as a part of an assessment of reducing the laser hazard distance using atmospheric attenuation within the ...
Gustafsson K. Ove S. +5 more
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Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Information and Organizational Self-Presentation: A Case Study of Kela’s Communication on Instagram
VAKKI PublicationsAs the use of social media has exploded in the first decades of the 21st century, institutions and public authorities have set up social media accounts in addition to established channels such as websites and e-services.
Jannika Lassus, Andreas Nord
doaj +1 more source
The mission characteristics of a newly implemented rural helicopter emergency medical service
BMC Emergency Medicine, 2018 Background Physician-staffed helicopter emergency services (HEMS) can provide benefit through the delivery of specialist competence and equipment to the prehospital scene and through expedient transport of critically ill patients to specialist care. This
Daniel Kornhall +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Automated retinal imaging and trend analysis – a tool for health monitoring
Clinical Ophthalmology, 2017 Karin Roesch, Tristan Swedish, Ramesh Raskar MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA Abstract: Most current diagnostic devices are expensive, require trained specialists to operate and gather static images with sparse ...
Roesch K, Swedish T, Raskar R
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