Results 41 to 50 of about 50,385 (254)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Membrane fluidity and lipid content of human spermatozoa selected by swim‐up method [PDF]

open access: yesInternational Journal of Andrology, 2001
In this work, we examined whether spermatozoa (spz) from normospermic fertile patients and selected by a swim‐up (S‐U) procedure had a particular membrane fluidity related to their maturity and their lipid content as compared with the sperm cells from the whole ejaculate (total sperm).
A, Force   +5 more
openaire   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Effect of Swim-Up and Percoll Treatment on Sperm Quality and In vitro Embryo Development in Yak

open access: yesJournal of Integrative Agriculture, 2013
This study was designed to determine the effect of different sperm preparation treatments on yak sperm quality and in vitro embryo development. Frozen-thawed semen samples were treated using swim-up or percoll gradient centrifugation methods.
Ben LIU, Yan CUI, Si-jiu YU
doaj   +1 more source

EFFECT OF SPERM SELECTION BY PERCOLL AND SWIM UP TECHNIQUES ON THE SEX RATIO OF RABBIT OFFSPRING [PDF]

open access: yesJournal of Animal and Poultry Production, 2013
This study was conducted to evaluate rabbit semen characterization before freezing and after thawing. Also, to determine the sex ratio of rabbit offspring’s after artificial insemination (AI) using semen selected by Percoll or swim up method.
A. Hussein
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Comparison of sperm parameters in swim up method with single and double washing

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2009
Background and Objective: There are different methods to improve sperm parmeters including swim up.Sperm washing is a basic step in This method during 2007.
Zahra Basirat (MD)   +2 more
doaj  

Can Microfluidics Improve Sperm Quality? A Prospective Functional Study

open access: yesBiomedicines
The same sperm selection techniques in assisted reproduction clinics have remained largely unchanged despite their weaknesses. Recently, microfluidic devices have emerged as a novel methodology that facilitates the sperm selection process with promising ...
Fernando Meseguer   +5 more
doaj   +1 more source

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