Results 71 to 80 of about 147,553 (266)

Swimming with the Shoal [PDF]

Cultural Studies of Science Education, 2017
This article responds to Yuli Rahmawati and Peter Charles Taylor’s piece and explores my role as a science teacher, science teacher educator and researcher in two contexts, Sierra Leone and Bhutan. In the first part of the article I reflect on my 3 years as a science teacher in Sierra Leone and demonstrate resonances with Yuli’s accounts of culture ...
openaire   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Sprinting to the top: comparing quality of distance variety and specialization between swimmers and runners

Frontiers in Sports and Active Living
ObjectivesTo compare performance progression and variety in race distances of comparable lengths (timewise) between pool swimming and track running. Quality of within-sport variety was determined as the performance differences between individual athletes'
Dennis-Peter Born, Dennis-Peter Born, Dennis-Peter Born, Michael Romann, Michael Romann, Jenny Lorentzen, David Zumbach, Andri Feldmann, Andri Feldmann, Jesús J. Ruiz-Navarro   +9 more
doaj   +1 more source

Swimming Physiology.

The Annals of physiological anthropology, 1992
Swimming takes place in a medium, that presents different gravitational and resistive forces, respiratory conditions and thermal stress compared to air. The energy cost of propulsion in swimming is high, but a considerable reduction occurs at a given velocity as result of regular swim training.
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Success factors in the training of elite coaches in high-performance swimming: Analysis from a focus group

PsychTech & Health Journal
This study aimed to identify the factors elite coaches consider most important in enhancing coach swimmers’ professional education and efficiency. A focus group was conducted with four Portuguese coaches recognized by the Portuguese Swimming Federation ...
António Vasconcelos Raposo, António Rosado   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Goggle-free swimming as autonomous water competence from the perspective of breath control on execution of a given distance

Scientific Reports
This study aimed to examine the ability of adolescents to maintain breathing rhythm while swimming with and without goggles, in the context of pedagogical interventions for implementation of water competence skills, rather than simply teaching swimming ...
Marek Rejman, Daria Rudnik, Robert Keig Stallman   +2 more
doaj   +1 more source

ASPECTS ON THE IMPLEMENTATION OF PSYCHOLOGICAL RESOURCES IN SWIMMING AT AN EARLY AGE THROUGH SURVEYS [PDF]

Annals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2018
The use of the survey, as a special category of investigation, on a specific professional category very well defined in the specialty of the activity, is extremely beneficial to improve the efficiency of swimming training at early age.
Burac Daniela Giconda, Furdu Dragoş
doaj