Results 61 to 70 of about 12,137 (217)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

TO SINK OR SWIM? [PDF]

Journal of Experimental Biology, 2008
There was an error published in J. Exp. Biol . 211(19) , [iv][1]. In this Outside JEB article, the first author of the following reference was incorrectly referred to as Yoshi Watanabe: Watanabe, Y., Wei, Q., Yang, D., Chen, X., Du, H., Yang, J., Sato, K., Naito, Y. and Miyazaki, N. (2008).
openaire   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Sprinting to the top: comparing quality of distance variety and specialization between swimmers and runners

Frontiers in Sports and Active Living
ObjectivesTo compare performance progression and variety in race distances of comparable lengths (timewise) between pool swimming and track running. Quality of within-sport variety was determined as the performance differences between individual athletes'
Dennis-Peter Born, Dennis-Peter Born, Dennis-Peter Born, Michael Romann, Michael Romann, Jenny Lorentzen, David Zumbach, Andri Feldmann, Andri Feldmann, Jesús J. Ruiz-Navarro   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Goggle-free swimming as autonomous water competence from the perspective of breath control on execution of a given distance

Scientific Reports
This study aimed to examine the ability of adolescents to maintain breathing rhythm while swimming with and without goggles, in the context of pedagogical interventions for implementation of water competence skills, rather than simply teaching swimming ...
Marek Rejman, Daria Rudnik, Robert Keig Stallman   +2 more
doaj   +1 more source

Success factors in the training of elite coaches in high-performance swimming: Analysis from a focus group

PsychTech & Health Journal
This study aimed to identify the factors elite coaches consider most important in enhancing coach swimmers’ professional education and efficiency. A focus group was conducted with four Portuguese coaches recognized by the Portuguese Swimming Federation ...
António Vasconcelos Raposo, António Rosado   +1 more
doaj   +1 more source

ASPECTS ON THE IMPLEMENTATION OF PSYCHOLOGICAL RESOURCES IN SWIMMING AT AN EARLY AGE THROUGH SURVEYS [PDF]

Annals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2018
The use of the survey, as a special category of investigation, on a specific professional category very well defined in the specialty of the activity, is extremely beneficial to improve the efficiency of swimming training at early age.
Burac Daniela Giconda, Furdu Dragoş
doaj