Results 41 to 50 of about 152,823 (267)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Focus on One Swimming Stroke or Compete in Multiple: How Much Specialization Is Needed to Become a World-Class Female Swimmer?

Journal of Functional Morphology and Kinesiology
Objectives: To investigate performance development and variety in swimming strokes of female swimmers from early junior to elite age. Methods: A total of 194,788 race times of female 200 m swimmers representing 77 nations were ranked at peak performance ...
Dennis-Peter Born, Jenny Lorentzen, Jesús J. Ruiz-Navarro, Thomas Stöggl, Michael Romann, Glenn Björklund   +5 more
doaj   +1 more source

Impact of in vitro digested zinc oxide nanoparticles on intestinal model systems

Particle and Fibre Toxicology, 2022
Background Zinc oxide nanoparticles (ZnO NP) offer beneficial properties for many applications, especially in the food sector. Consequently, as part of the human food chain, they are taken up orally. The toxicological evaluation of orally ingested ZnO NP
Anna Mittag, Alina Singer, Christian Hoera, Martin Westermann, Alexander Kämpfe, Michael Glei   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Competition-Based Success Factors During the Talent Pathway of Elite Male Swimmers

Frontiers in Sports and Active Living, 2020
Marginal differences in race results between top swimmers have evoked the interest in competition-based success factors of long-term athlete development.
Dennis-Peter Born, Dennis-Peter Born, Ishbel Lomax, Stephan Horvath, Elena Meisser, Elena Meisser, Philipp Seidenschwarz, Philipp Seidenschwarz, David Burkhardt, Michael Romann   +9 more
doaj   +1 more source

Effects of the Basic Period in Swimming Training with the Age Group [PDF]

Sport Mont, 2019
Development of aerobic capacity and endurance is important part of basic period in swimming training for age groups. The focus of this study was monitoring the progress of a group of 17 male swimmers, aged between 12 to 14 from HAPK Mladost, Zagreb. They
Goran Leko, Klara Siljeg, Tatjana Greguranic   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The kinematic profile of ventral swimming start: sex diversity

Frontiers in Physiology, 2023
It has been suggested that sex distinctions in physiology may affect the swimming performance of each sex differently. Yet, sex-based performance dependency has not been taken into consideration by most of the researchers evaluating swimming start ...
Daria Malgorzata Rudnik, Daria Malgorzata Rudnik, Marek Rejman, Joao Paulo Vilas-Boas, Joao Paulo Vilas-Boas   +4 more
doaj   +1 more source

TO SINK OR SWIM? [PDF]

Journal of Experimental Biology, 2008
There was an error published in J. Exp. Biol . 211(19) , [iv][1]. In this Outside JEB article, the first author of the following reference was incorrectly referred to as Yoshi Watanabe: Watanabe, Y., Wei, Q., Yang, D., Chen, X., Du, H., Yang, J., Sato, K., Naito, Y. and Miyazaki, N. (2008).
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source