Results 61 to 70 of about 8,554,084 (253)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Hydrophobicity Influence on Swimming Performance of Magnetically Driven Miniature Helical Swimmers

Micromachines, 2019
Helical microswimmers have been involved in a wide variety of applications, ranging from in vivo tasks such as targeted drug delivery to in vitro tasks such as transporting micro objects.
Chengwei Ye, Jia Liu, Xinyu Wu, Ben Wang, Li Zhang, Yuanyi Zheng, Tiantian Xu   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Kinetics, kinematics, and performance modeling of two arm swing techniques in the swimming kick-start

Scientific Reports
This experimental study investigated the effect of two arm swing techniques on kinematic and kinetic variables during the swimming kick-start. Twelve elite male swimmers performed starts using forward and butterfly arm swing techniques.
Stefan Szczepan, Zofia Wróblewska, Daria Rudnik, Faye Perkins, Peter Bodary, Michael Bottom   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

In-channel experiments on vertical swimming with bacteria-like robots [PDF]

, 2013
Bio-inspired micro-robots are of great importance as to implement versatile microsystems for a variety of in vivo and in vitro applications in medicine and biology.
Tabak, Ahmet Fatih, Ahmet Fatih Tabak, Yeşilyurt, Serhat, Serhat Yesilyurt   +3 more
core   +2 more sources

Sex differences in youth elite swimming.

PLoS ONE, 2019
BackgroundThe timing and magnitude of sex differences in athletic performance during early human development, prior to adulthood, is unknown.ObjectiveTo compare swimming velocity of boys and girls for all Olympic-length freestyle swimming events to ...
Jonathon W Senefeld, Andrew J Clayburn, Sarah E Baker, Rickey E Carter, Patrick W Johnson, Michael J Joyner   +5 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Physical performance determinants in competitive youth swimmers: a systematic review

BMC Sports Science, Medicine and Rehabilitation
Background Youth swimming performance is determined by several physiological, biomechanical and anthropometric characteristics. This review aimed to identify physical performance determinants of youth swimming performance, assessing strength, power ...
Todd Price, Giuseppe Cimadoro, Hayley S Legg   +2 more
doaj   +1 more source