Results 41 to 50 of about 8,454,807 (248)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Generation of widely tunable picosecond pulses with large SMSR by externally injecting a gain-switched dual laser source [PDF]
, 2004 The authors demonstrate a procedure of generating picosecond optical pulses that are tunable over a wide wavelength range (65 nm) and have very high spectral purity side-mode suppression ratio [(SMSR)>60 dB].
Anandarajah, Prince M. +2 more
core +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2013 We report the generation of short, transform-limited, ~18 ps optical pulses from an external fiber Bragg grating (FBG) stabilized semiconductor laser diode.
Shaif-ul Alam +9 more
core +1 more source
A High Power Factor Symmetrical Switched-Mode Power Supply.
Revista Tecnologia, 2009 This paper proposes a switched-mode power supply (SMPS) with power factor correction. A preregulator boost converter is employed in order to obtain universal line voltage and reduced harmonic content of the input current. Two dc/dc forward converters are
Fernando Lessa Tofoli +1 more
doaj
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Automatika, 2023 This research work emphasizes on the development of a unique high-gain BOCUK DC-DC converter for Switched Mode Power Supply (SMPS) applications. The high-gain BOOST-CUK (BOCUK) DC-DC converter combines the benefits of both Boost and Cuk converters for ...
L. Annie Isabella +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Switched power supply for flowmeter
, 2023 Cílem této bakalářské práce je popsat různé topologie spínaných zdrojů, porovnat je a vyvinout specializovaný spínaný zdroj topologie flyback pro průtokoměr. Významnou vlastností zdroje je široký rozsah vstupního napětí.
Rydval, Štěpán
core +1 more source
IMPLEMENTATION OF A SWITCHED POWER SUPPLY FOR THE PLASMA ELECTROLYTIC OXIDATION TECHNIQUE
Revista de la Facultad de Ciencias, 2017 A switched-mode power supply was implemented for using in the Plasma Electrolytic Oxidation (PEO) technique. The electronic devices are inexpensive and ordinarily used, which facilitates the construction of the system.
Fernando Gordillo-Delgado +2 more
doaj +1 more source