Results 21 to 30 of about 4,265 (217)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

48 V to 1 V DC-DC Converter Based on Cascade/Ladder Connected Switched Capacitor Cells

Eletrônica de Potência
This paper proposes a cascade/ladder switched capacitor converter integrated with an interleaved synchronous buck converter to provide a 48 V to 1 V conversion for data center applications.
Neilor C. Dal Pont, Jessika M. de Andrade, Chokkalingam Bharatiraja, Brad Lehman, Telles B. Lazzarin   +4 more
doaj   +1 more source

SWITCHED CAPACITOR FILTER DESIGN SIMULATION

Diyala Journal of Engineering Sciences, 2009
The filter is very important tool in electrical circuits, it is the maen part at communication devices. The design operation of any filter depends upon the frequency, bandwidth and gain. In this paper we will introduce a filter has specialist in design,
Abdul-jabbar K. Hummady
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Performance evaluation of aluminum/phosphate cell for powering small electronic devices

Sensing and Bio-Sensing Research, 2015
We report on an innovative membrane-free aluminum/phosphate cell based on the activation of aluminum (Al) as anodic material using ZnO nanocrystal in phosphate rich electrolyte that is capable of generating sufficient power to power a light-emitting ...
Gymama Slaughter, Joshua Sunday
doaj   +1 more source

MMC Based Hybrid Switched Capacitor DC-DC Converter

IEEE Open Journal of Power Electronics, 2022
Aiming to address the growth and the integration of renewable sources and electronic loads, different types of dc-dc topologies with specific features have been proposed, going from medium frequency isolated Modular Multilevel Converter to Switched ...
Marcus Vieira Soares, Yales Romulo de Novaes   +1 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Hybrid Switched Capacitor Three Winding Coupled Inductor High Step-Up DC-DC Converter

IEEE Access
Switched capacitor cells have been studied in recent years. These approaches allow different new topologies to be generated. One such technique is the hybrid converter, where a coupled inductor and switched capacitor can be combined. Thus, in this paper,
Antonio Manuel Santos Spencer Andrade, Pablo Henrique Costa da Silva Bernardo Loureiro, Ademir Toebe   +2 more
doaj   +1 more source