Results 31 to 40 of about 137,408 (266)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai   +4 more
wiley   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Gain Scheduling Approach of Delayed Control with Application to Aircraft Wing in Wind Tunnel

open access: yesMathematics
The objective of this work is to study the equilibrium stability of a switched linear model with time-delayed control and additive disturbances, that in subsidiary represents the control of wing vibrations in the presence of the turbulence disturbances ...
Daniela Enciu, Adrian Toader, Ioan Ursu
doaj   +1 more source

A Switching-Method for nonlinear systems

open access: yesJournal of Computational and Applied Mathematics, 1996
The paper is intended to present an iterative method for the solution of nonlinear equations. This method consist in combining a direct search method and a damped approximate Newton method in order to avoid the computation of the Jacobian. The obtained hybrid method (called switching-method, due to the fact that at each iteration just one of the above ...
BELLAVIA, STEFANIA   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Time-Varying Tan-Type Barrier Lyapunov Function-Based Adaptive Fuzzy Control for Switched Systems With Unknown Dead Zone

open access: yesIEEE Access, 2019
This paper investigates the output constraint problem for switched uncertain nonlinear systems with unknown dead-zone input. The system output is constrained by a time-varying bound, and the time-varying Barrier Lyapunov Function (BLF) is employed to ...
Li Tang, Aiqing Chen, Dongjuan Li
doaj   +1 more source

Switched Systems as Hybrid Programs

open access: yesIFAC-PapersOnLine, 2021
Long version of paper at ADHS 2021 (7th IFAC Conference on Analysis and Design of Hybrid Systems, July 7-9, 2021)
Tan, Yong Kiam, Platzer, André
openaire   +4 more sources

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