Results 51 to 60 of about 712,860 (302)

How to switch a master switch

eLife, 2013
The crystal structure of a nucleotide exchange factor in white blood cells reveals an autoinhibitory mechanism that reinforces the switch-like behaviour of the signalling protein Ras.
Hein, Christopher, Wittinghofer, Alfred, Dötsch, Volker   +2 more
openaire   +4 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

CSVRF: A CAM‐based popularity‐aware egress group‐caching scheme for SVRF‐based packet forward engines

IET Communications
As a key component of high‐performance switches and routers, the packet forwarding engine (PFE) is mainly responsible for selecting the appropriate output port for tens of thousands of packets within an extremely short time frame.
Ruisi Wu, Wen‐Kang Jia
doaj   +1 more source

Start/stop switches for testing detonation velocity of explosives [PDF]

, 1975
Printed-circuit process produces ordnance-initiated start/stop switches.
Grimes, W. E., Wise, J. P.
core   +1 more source

Transmitter Architectures Based on Near-Field Direct Antenna Modulation [PDF]

, 2008
A near-field direct antenna modulation (NFDAM) technique is introduced, where the radiated far-field signal is modulated by time-varying changes in the antenna near-field electromagnetic (EM) boundary conditions. This enables the transmitter to send data
Babakhani, Aydin, Hajimiri, Ali, Rutledge, David B.   +2 more
core   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

An Electrically Actuated DC-to-11-GHz Liquid-Metal Switch

IEEE Access, 2018
A liquid-metal RF shunt switch is presented that combines a dielectric spacer over the RF path with electrolyte-filled capillary troughs to facilitate low-power electrical actuation.
Matthew R. Moorefield, Ryan C. Gough, Aaron T. Ohta, Wayne A. Shiroma   +3 more
doaj   +1 more source

Statins: to switch or not to switch? [PDF]

Prescriber, 2008
Abstract Two doctors argue for and against the policy of switching patients from expensive branded statins to lower‐cost generic formulations in order to reduce NHS prescribing costs.
David Goldsmith, Martin Duerden
openaire   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source