Results 51 to 60 of about 20,851 (255)

Condition Monitoring of Railway Crossing Geometry via Measured and Simulated Track Responses

Sensors, 2022
This paper presents methods for continuous condition monitoring of railway switches and crossings (S&C, turnout) via sleeper-mounted accelerometers at the crossing transition. The methods are developed from concurrently measured sleeper accelerations and
Marko D. G. Milosevic, Björn A. Pålsson, Arne Nissen, Jens C. O. Nielsen, Håkan Johansson   +4 more
doaj   +1 more source

Architectures and Buffering for All-Optical Packet-Switched Cross-Connects [PDF]

Photonic Network Communications, 2006
This paper considers the performance of an all-optical packet-switched cross-connect. All-optical header processing and all-optical routing are implemented in the cross-connect architectures. The main metric considered to measure the performance is the packet loss ratio for the buffering. This is influenced primarily by three factors.
Geldenhuys, R., Liu, Y., Hill, M.T., Khoe, G.D., Leuschner, F.W., Dorren, H.J.S.   +5 more
openaire   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Two railway circuits: a universal circuit and an NP-difficult one [PDF]

Computer Science Journal of Moldova, 2001
In this paper, first we construct a railway circuit based on three types of switches and on crossings. Such a circuit is able to simulate the computation of any Turing machine, in particular of a universal one. That result was proved by Ian Stewart in [3]
Maurice Margenstern
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Virtual Knot Cobordism

, 2014
This paper defines a theory of cobordism for virtual knots and studies this theory for standard and rotational virtual knots and links. Non-trivial examples of virtual slice knots are given. Determinations of the four-ball genus of positive virtual knots
Kauffman, Louis H.
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Physical Insights into Molecular Sensors, Molecular Logic Gates, and Photosensitizers in Photodynamic Therapy

Journal of Chemistry, 2019
In this article, the importance of charge/electron transfer in two rapidly growing areas of science is highlighted. In the field of molecular sensors, it plays a considerable role on the detection of molecular systems to serve as fluorescence sensors ...
Demeter Tzeli, Ioannis D. Petsalakis
doaj   +1 more source