Results 71 to 80 of about 35,558 (271)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A Common Switch used by Plants and Animals [PDF]

open access: yesCell, 2004
AbstractComparisons of plant and animal development usually highlight their differences. The discovery that a kinase of the MAPKK class plays a key role in cell specification at the first division of the Arabidopsis embryo suggests that there may be similarities based on a common logic.
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Undisturbed Switching Control Method of Superheated Steam Temperature Systems

open access: yesComplexity, 2019
In this paper, a new type of superheated steam temperature switching control system for thermal power plants is presented. A single neuron adaptive PSD (Proportional Sum Differential) predictive controller is designed. The DCS (Distributed Control System)
Lei Yu
doaj   +1 more source

Selection and dimensioning of disconnecting switch

open access: yes, 2019
Ovaj završni rad detaljno prikazuje rastavljače kao elemente rasklopnog postrojenja. U teorijskom dijelu opisani su osnovni pojmovi vezani za rastavljače, te izvedbe rastavljača.
Radoš, Ana
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Changes in Farm Supply Voltage Caused by Switching Operations at a Wind Turbine

open access: yesEnergies
Renewable electricity sources are now widely used worldwide. Currently, the most common sources are those that use energy contained in biomass, water, sun, and wind. When connected to a medium-voltage grid, individual wind power plants must meet specific
Jacek Filipkowski   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Intelligent system to improve the power switch-on and switchoff procedures in industrial plants

open access: yesRevue de Métallurgie, 2006
In order to improve the safety and reduce plant shut down time for scheduled maintenance works, Aceralia is developing and testing on its HSM at Aviles an application that ensures that the selected equipment is correctly and safely powered down. This application also serves updated information regarding the current status of maintenance works and ...
López Rodríguez, Antonio Miguel   +4 more
openaire   +2 more sources

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