Results 41 to 50 of about 25,234 (258)

Analysis of W-band traveling-wave tube based upon slotted sine waveguide slow wave structure

open access: yesAIP Advances, 2021
In this paper, a W-band traveling-wave tube (TWT) is proposed by combining the slotted sine waveguide (SSWG) slow-wave structure (SWS) with the cylindrical electron beam.
Zhang Luqi   +6 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

ODESWS, A Semantic Web Service Development [PDF]

open access: yes, 2004
ODE SWS is a development environment to design Semantic Web Services (SWS) at the knowledge level. ODE SWS describe the service following a problem-solving approach in which the SWS are modeled using tasks, to represent the SWS functional features, and ...
González-Cabero, R.   +2 more
core  

Design, fabrication, and testing of CVI-SiC/SiC turbine blisk under different load spectrums at elevated temperature

open access: yesHigh Temperature Materials and Processes, 2022
In this article, design, fabrication, and testing of SiC/SiC turbine blisk with the fiber’s preform of Spider Web Structure (SWS) subjected to different load spectrums at elevated temperature are conducted. Micro-CT scans are conducted to show the fibers
Guo Xiaojun   +6 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Interaction between slow wave sleep and elevated office blood pressure in non-hypertensive obstructive sleep apnea patients: a cross-sectional study

open access: yesBlood Pressure, 2023
Purpose: Reduced slow wave sleep (SWS) has been linked to hypertension in some studies. The aim of the study is to investigate the association between SWS and office blood pressure (BP) in non-hypertensive obstructive sleep apnea (OSA).
Ning Xia   +4 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Release of Nutrients and Organic Matter from River Floodplain Habitats: Simulating Seasonal Inundation Dynamics

open access: yes, 2013
River floodplains form a complex mosaic of aquatic, semi-aquatic, and terrestrial habitats. While spatially distinct, these habitats are connected through water, carbon and nutrients, and thus ecosystem processes in one habitat type may have ...
Joana Rosado   +9 more
core   +1 more source

From macro to micro: slow-wave sleep and its pivotal health implications

open access: yesFrontiers in Sleep
Research on slow-wave sleep (SWS) began almost a century ago, not long after the discovery of electroencephalography. From maintaining homeostasis to memory function, the pivotal role of SWS in health has been established.
Toru Ishii   +7 more
doaj   +1 more source

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