Results 41 to 50 of about 1,120 (154)

Treatment of Sydenham's Chorea: A Review of the Current Evidence

Tremor and Other Hyperkinetic Movements, 2017
Background: Sydenham’s chorea (SC), the neurologic manifestation of rheumatic fever, remains the most prevalent form of chorea in children. Suggested treatments of chorea in SC include prophylactic penicillin, symptomatic (antipsychotic and ...
Shannon L. Dean, Harvey S. Singer
doaj   +1 more source

Requirements for a Robust Animal Model to Investigate the Disease Mechanism of Autoimmune Complications Associated With ARF/RHD

Frontiers in Cardiovascular Medicine, 2021
The pathogenesis of Acute Rheumatic Fever/Rheumatic Heart Disease (ARF/RHD) and associated neurobehavioral complications including Sydenham's chorea (SC) is complex. Disease complications triggered by Group A streptococcal (GAS) infection are confined to
Rukshan A. M. Rafeek, Suchandan Sikder, Suchandan Sikder, Adam S. Hamlin, Nicholas M. Andronicos, David J. McMillan, David J. McMillan, Kadaba S. Sriprakash, Kadaba S. Sriprakash, Natkunam Ketheesan   +9 more
doaj   +1 more source

Myocarditis Following Invasive Group A Streptococcus Infection: Important Differential Diagnostic Distinctions

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Nonrheumatic streptococcal pharyngitis−associated myocarditis presents as acute myocarditis within days of Group A Streptococcus pharyngitis, typically resolving with antibiotics and minimal sequelae. It is thought to result from direct bacterial toxin injury rather than autoimmunity.
Jonathan M. Oxman, Michael Bourne, David C. Perlman, Nicholas Sells, Priya Gusain   +4 more
wiley   +1 more source

An update on the treatment of Sydenham’s chorea: the evidence for established and evolving interventions

Therapeutic Advances in Neurological Disorders, 2010
Over 320 years after Thomas Sydenham described the condition labelled Sydenham’s chorea, it remains poorly understood. The disorder is an antineuronal antibody-mediated neuropsychiatric disorder caused by a poststreptococcal, autoimmune condition ...
Kathleen G. Walker, Jo M. Wilmshurst
doaj   +1 more source

Secondary enuresis associated with chorea in a Nigerian girl

Indian Journal of Psychological Medicine, 2014
Enuresis is a distressing psycho-social disorder. It is often a neglected disorder, and its effect on the psychosocial development of a child is often overlooked, especially in those of low socio-economic status.
Ibrahim Aliyu
doaj   +1 more source

Dopamine receptor autoantibodies correlate with symptoms in Sydenham's chorea. [PDF]

PLoS ONE, 2013
BackgroundSydenham chorea (SC), a neuropsychiatric sequela of group-A streptococcal infection, is associated with basal ganglia autoantibodies. Although autoantibodies have been proposed in neuropsychiatric disorders, little evidence has been shown to ...
Hilla Ben-Pazi, Julie A Stoner, Madeleine W Cunningham   +2 more
doaj   +1 more source

Postpump Chorea After Pediatric Cardiac Surgery: Exploring Causes and Treatment

Journal of Cardiac Surgery, Volume 2026, Issue 1, 2026.
Introduction Postpump chorea is a rare but potentially disabling movement disorder that arises days to weeks after cardiopulmonary bypass, most often following deep hypothermic circulatory arrest in pediatric patients undergoing repair of complex congenital heart defects. Clinically, postpump chorea presents as involuntary, nonrhythmic, choreiform, and
Jad Abdul Khalek, Karim Kanbar, Fadi Bitar, Mariam Arabi, Randy Stevens   +4 more
wiley   +1 more source

A Preliminary Study of Heart and Brain Autoreactivity After Group A Streptococcal Carbohydrate Antigen Immunization in Rabbits

Proceedings
There is current interest in the group A streptococcal carbohydrate as a vaccine antigen, and previous studies have suggested that it may induce host tissue cross-reactive autoantibodies which react with heart and brain autoantigens and which are present
Madeleine W. Cunningham, Kathleen Alvarez, Rebecca Bentley, A. D. Sarma, C. Kamat, Marc LaForce, Francis Michon, S. S. Pisal   +7 more
doaj   +1 more source

Spasmodic Dysphonia

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 11, Issue 4, Page 548-567, December 2025.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

Sydenham’s Chorea Therapy

Pediatric Neurology Briefs, 1988
Five patients with chorea successfully treated with carbamazepine at plasma levels of 6.5 - 8.8 mcg/ml are reported from the Dept of Pediatrics, Child Neurology and EEG Service, Hospital Infantil Vall dHebron, Autonomous University, Barcelona, Spain.
openaire   +4 more sources