Results 51 to 60 of about 55,219 (268)

Debugging Multithreaded Programs as if They Were Sequential

open access: yesIEEE Access, 2018
Debugging multithread programs is extremely difficult because the basic assumption that underlies sequential program debugging, that is, the program behavior is deterministic under a fixed input, is no longer valid due to the nondeterminism attributed to
Xiaodong Zhang   +6 more
doaj   +1 more source

Symbolic Backwards-Reachability Analysis for Higher-Order Pushdown Systems [PDF]

open access: yesLogical Methods in Computer Science, 2008
Higher-order pushdown systems (PDSs) generalise pushdown systems through the use of higher-order stacks, that is, a nested "stack of stacks" structure.
Matthew Hague, C. -H. Luke Ong
doaj   +1 more source

Efficient symbolic analysis of programs

open access: yesJournal of Computer and System Sciences, 1986
This paper is concerned with constructing, for each expression in a given program text, a symbolic expression whose value is equal to the value of the text expression for all executions of the program. A cover is a mapping from text expressions to such symbolic expressions.
John H. Reif, Harry R. Lewis
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Algorithmics, Possibilities and Limits of Ordinal Pattern Based Entropies

open access: yesEntropy, 2019
The study of nonlinear and possibly chaotic time-dependent systems involves long-term data acquisition or high sample rates. The resulting big data is valuable in order to provide useful insights into long-term dynamics.
Albert B. Piek   +2 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Program state optimal method based on variable symbolic relation analysis

open access: yesTongxin xuebao, 2018
Program analysis is the prime method to program property analysis,which is widely used in the domain of parameter dependent relation,path coverage and test case generation,and a lot of progress has been made.Current program analysis is based on the ...
Xi GUO, Pan WANG
doaj   +2 more sources

Revisiting the Characterization of Resting Brain Dynamics with the Permutation Jensen–Shannon Distance

open access: yesEntropy
Taking into account the complexity of the human brain dynamics, the appropriate characterization of any brain state is a challenge not easily met. Actually, even the discrimination of simple behavioral tasks, such as resting with eyes closed or eyes open,
Luciano Zunino
doaj   +1 more source

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