Results 31 to 40 of about 593,480 (290)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Translation as Adaptation for Language Pedagogy

open access: yesLinguaculture, 2014
This paper explores, within an ecological perspective on language learning (cf. van Lier 2004), the valuable role that translation as adaptation can play in mediating and making sense of cross-cultural experiences in the multilingual language classroom ...
Laviosa Sara
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Abridged Symbolic Representation of Time Series for Clustering

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2019
In recent years a couple of methods aimed at time series symbolic representation have been introduced or developed. This activity is mainly justified by practical considerations such memory savings or fast data base searching.
Jerzy Korzeniewski
doaj   +1 more source

On Symbolic Ultrametrics, Cotree Representations, and Cograph Edge Decompositions and Partitions

open access: yes, 2015
Symbolic ultrametrics define edge-colored complete graphs K_n and yield a simple tree representation of K_n. We discuss, under which conditions this idea can be generalized to find a symbolic ultrametric that, in addition, distinguishes between edges and
A Burstein   +17 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Conformant Planning via Symbolic Model Checking

open access: yes, 2011
We tackle the problem of planning in nondeterministic domains, by presenting a new approach to conformant planning. Conformant planning is the problem of finding a sequence of actions that is guaranteed to achieve the goal despite the nondeterminism of ...
Cimatti, A., Roveri, M.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The impact of musical training in symbolic and non-symbolic audiovisual judgements of magnitude.

open access: yesPLoS ONE, 2022
Quantity estimation can be represented in either an analog or symbolic manner and recent evidence now suggests that analog and symbolic representation of quantities interact.
Nikos Chalas   +3 more
doaj   +1 more source

Analysis of The Student's Ability to Interconnect Macro-Submicro-Symbolic Representation on Electrolyte Solution Concept

open access: yesEduChemia, 2023
A comprehensive understanding of chemistry requires thinking using three levels of interconnected representation: macroscopic, submicroscopic, and symbolic.
Indah Langitasari, Babang Robandi
doaj   +1 more source

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