Results 51 to 60 of about 47,816 (292)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A Library for Composite Symbolic Representations [PDF]
, 2001 In this paper, we present the design and the implementation of a composite model checking library. Our tool combines different symbolic representations, such as BDDs for representing boolean logic formulas and polyhedral representations for linear arithmetic formulas, with a single interface.
Tuba Yavuz-Kahveci +2 more
openaire +1 more source
Social gaze and symbolic skills in typically developing infants and children with autism [PDF]
, 2001 The aim of this thesis was to investigate, through two observational studies, the relation among social gaze, play and language in 27 typically developing infants (study 1) and 18 young children with autism (study 2).
Gagliano, Antonino
core
MPEG Symbolic Music Representation
, 2008 The evolution of digital communication devices and formats has recently produced fundamental changes in the practical approach to music representation and notation, transforming them from a simple visual coding model for sheet music into a composite tool
Pierfrancesco Bellini +2 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The Challenge of Learning Symbolic Representations. [PDF]
, 2023 Learning abstract representations from perceptual stimuli is a natural task for humans, but a real challenge for AI systems. In the vast majority of cases, in fact, systems that have to deal with symbol manipulation, like in reasoning or planning, do not need to also learn the symbols they operate on, but these are typically assumed to be given by a ...
Lorello L. S., Lippi M.
openaire +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Translation as Adaptation for Language Pedagogy
Linguaculture, 2014 This paper explores, within an ecological perspective on language learning (cf. van Lier 2004), the valuable role that translation as adaptation can play in mediating and making sense of cross-cultural experiences in the multilingual language classroom ...
Laviosa Sara
doaj +1 more source
EduChemia, 2023 A comprehensive understanding of chemistry requires thinking using three levels of interconnected representation: macroscopic, submicroscopic, and symbolic.
Indah Langitasari, Babang Robandi
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source