Results 61 to 70 of about 47,816 (292)

The impact of musical training in symbolic and non-symbolic audiovisual judgements of magnitude.

open access: yesPLoS ONE, 2022
Quantity estimation can be represented in either an analog or symbolic manner and recent evidence now suggests that analog and symbolic representation of quantities interact.
Nikos Chalas   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Semiotic Mathematics Representation Ability Based on Symbolic in Solving SPLSV Problems in Class VII Students

open access: yesTa'dib
Mathematical semiotic representation is the ability to analyze and express mathematical ideas or notions of a phenomenon and everyday problem situations into the form of signs, images, symbols, and symbols that represent them and provide meaning and ...
Dwi Tri Fresti Firnanda, Indah Wahyuni
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Generative Structural Representation of Tonal Music. [PDF]

open access: yes, 2005
The usefulness and desirability of representation schemes which explicitly show musical structure has often been commented upon. A particular aim of music theory and analysis has been to describe and derive musical structure, and this article discusses ...
Marsden, Alan A.
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

ANALISIS KEMAMPUAN REPRESENTASI MATEMATIS SISWA DITINJAU DARI KECEMASAN MATEMATIKA [ANALYSIS OF STUDENTS' MATHEMATICAL REPRESENTATION ABILITY IN TERMS OF MATH ANXIETY]

open access: yesJOHME: Journal of Holistic Mathematics Education
The purpose of this research is to describe the profile of students' mathematical representation ability in terms of math anxiety. This research method is descriptive qualitative method.
Nur Lisa Andriani, Nur Fauziyah
doaj   +1 more source

Symbolic Representation and Classification of N = 1 Supersymmetric Evolutionary Equations [PDF]

open access: yes, 2017
We extend the symbolic representation to the ring of N = 1 supersymmetricdifferential polynomials, and demonstrate that operations on the ring, suchas the super derivative, Fr´echet derivative, and super commutator, can becarried out in the symbolic way.
Tian, Kai   +3 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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