Results 51 to 60 of about 594,677 (236)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Differentiable Genetic Programming
, 2016 We introduce the use of high order automatic differentiation, implemented via the algebra of truncated Taylor polynomials, in genetic programming. Using the Cartesian Genetic Programming encoding we obtain a high-order Taylor representation of the ...
Biscani, Francesco +2 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Ta'dibMathematical semiotic representation is the ability to analyze and express mathematical ideas or notions of a phenomenon and everyday problem situations into the form of signs, images, symbols, and symbols that represent them and provide meaning and ...
Dwi Tri Fresti Firnanda, Indah Wahyuni
doaj +1 more source
Representación Simbólica de Preguntas: el proyecto ReSim [PDF]
Sintagma, 2006 Symbolic representation of questions: The ReSim Project. In this article we present the ReSim project: the symbolic representation of questions. The aim of this project was to create an automatic system capable of representing natural language questions ...
Ana Fernández Montraveta +2 more
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Notes on narrative, cognition, and cultural evolution
Sign Systems Studies, 2016 Drawing on non-Darwinian cultural-evolutionary approaches, the paper develops a broad, non-representational perspective on narrative, necessary to account for the narrative “ubiquity” hypothesis.
Marina Grishakova, Siim Sorokin
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FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Translation as Adaptation for Language Pedagogy
Linguaculture, 2014 This paper explores, within an ecological perspective on language learning (cf. van Lier 2004), the valuable role that translation as adaptation can play in mediating and making sense of cross-cultural experiences in the multilingual language classroom ...
Laviosa Sara
doaj +1 more source
Symbolic Representation of Finite Automata [PDF]
, 2014 V~oblasti formální analýzy se často setkáváme s~konečnými automaty s~velkým množstvím stavů nad velkými abecedami. Jejich explicitní reprezentace může vyústit ve stavovou explozi a~tento problém může být vyřešen použitím symbolické reprezentace schopné ...
Chromečka, Jiří
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