Results 41 to 50 of about 412,934 (237)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Neural network-based symmetric encryption algorithm with encrypted traffic protocol identification [PDF]

PeerJ Computer Science
Cryptography is a cornerstone of power grid security, with the symmetry and asymmetry of cryptographic algorithms directly influencing the resilience of power systems against cyberattacks.
Jiakai Hao, Ming Jin, Yuting Li, Yuxin Yang   +3 more
doaj   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Security of signed ELGamal encryption [PDF]

, 2005
Assuming a cryptographically strong cyclic group G of prime order q and a random hash function H, we show that ElGamal encryption with an added Schnorr signature is secure against the adaptive chosen ciphertext attack, in which an attacker can freely use
Jakobsson, Markus, Schnorr, Claus Peter
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Amortized Threshold Symmetric-key Encryption [PDF]

, 2021
Threshold cryptography enables cryptographic operations while keeping the secret keys distributed at all times. Agrawal et al. (CCS\u2718) propose a framework for Distributed Symmetric-key Encryption (DiSE).
Sivanarayana Gaddam, Mihai Christodorescu, Pratyay Mukherjee, Rohit Sinha   +3 more
core   +1 more source

Improved SAFER Plus Algorithm Using the Odd-Squared New Mersenne Number Transform

Proceedings of the International Conference on Applied Innovations in IT
Encryption secures data by transforming it into unreadable information (ciphertext) that can only be read by authorized receivers, who then convert the unclear data back into the original plaintext.
Abdulmutalib A-Wahab Hussein, Lujain Sabah Abdulla, Mounir Taha Hamood   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Implementasi Protokol Diffie-Hellman Dan Algoritma RC4 Untuk Keamanan Pesan SMS

IJCCS (Indonesian Journal of Computing and Cybernetics Systems), 2015
Abstrack— SMS now becomes such a need for cellular phone users to communicate to other people. But the cellular phone users do not realize that the sent messages could be intercepted or changed by an unwanted party.
Decky Hendarsyah, Retantyo Wardoyo
doaj   +1 more source