Results 81 to 90 of about 5,923,679 (293)
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Extended algebraic immunity of symmetric Boolean function
Boolean functions with optimal algebraic immunity play an important role in stream ciphers.Based on the univariate polynomial representation of Boolean functions,a construction of Boolean functions with maximum extended algebraic immunity (EAI) is ...
Gao-fei WU +3 more
doaj +2 more sources
Generalized matrix functions, determinant and permanent
Introduction Since linear and multilinear algebra has many applications in different branches of sciences, the attention of many mathematicians has been attracted to it in recent decades. The determinant and the permanent are the most important functions
Mohammad Hossein Jafari, Ali Reza Madadi
doaj
SOME TYPICAL PROPERTIES OF SYMMETRICALLY CONTINUOUS FUNCTIONS, SYMMETRIC FUNCTIONS AND CONTINUOUS FUNCTIONS [PDF]
The existence of a bounded measurable (periodic) symmetrically continuous function and a bounded measurable symmetric function on an interval \([a,b]\) which are discontinuous at points of a set of power \(c\) was proved by D. Preiss and T.-C. Tran, respectively. It is used to show, in a straightforward way, that the functions with these properties are
openaire +3 more sources
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Regular symmetric arrays for non-symmetric functions [PDF]
A new class of non-totally symmetric functions which can be represented as simple regular symmetric arrays without redundancy is identified. Regular circuits are becoming crucially important for deep submicron technologies, which needs new layout approaches to fully utilized their potential.
openaire +2 more sources

