Results 41 to 50 of about 2,742 (258)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Symmetric and generating functions of generalized (p,q)-numbers

open access: yesKuwait Journal of Science, 2021
In this paper, we will firstly define a new generalization of numbers (p, q) and then derive the appropriate Binet's formula and generating functions concerning (p,q)-Fibonacci numbers, (p,q)- Lucas numbers, (p,q)-Pell numbers, (p,q)-Pell Lucas numbers, (p,q)-Jacobsthal numbers and (p,q)-Jacobsthal Lucas numbers.
Nabiha Saba   +2 more
openaire   +3 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Certain fixed point results for novel contractions with applications to variational inequalities, economic growth and market equilibrium via fractional differential equations

open access: yesBoundary Value Problems
This paper presents a new approach to analyze the market equilibrium and economic growth via enriched ( S ˚ , θ , Z ) $(\mathring{\mathscr{S}}, \theta , \mathscr{Z})$ -contractions and their generalizations.
Mati ur Rahman   +3 more
doaj   +1 more source

Noncommutative Symmetric Functions and Lagrange Inversion II: Noncrossing partititions and the Farahat-Higman algebra

open access: yes, 2022
35 pagesWe introduce a new pair of mutually dual bases of noncommutative symmetric functions and quasi-symmetric functions, and use it to derive generalizations of several results on the reduced incidence algebra of the lattice of noncrossing partitions.
Thibon, Jean-Yves   +1 more
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Symmetric functionals on simply generated symmetric spaces

open access: yesJournal of Mathematical Analysis and Applications
In the present paper we suggest a construction of symmetric functionals on a large class of symmetric spaces over a semifinite von Neumann algebra. This approach establishes a bijection between the symmetric functionals on symmetric spaces and shift-invariant functionals on the space of bounded sequences.
Levitina, Galina, Usachev, Alexandr
openaire   +2 more sources

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