Results 211 to 220 of about 123,872 (245)

autoscoRA: Deep Learning to Automate Sharp/van der Heijde Scoring of Radiographic Damage in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Regular imaging by conventional radiography to assess for joint damage is a cornerstone in the management of rheumatoid arthritis. Scoring systems to quantify such damage, such as the widely used Sharp/van der Heijde (SvdH) score, are limited by the requirement of time and experienced staff as well as intra‐ and interrater variability.
Thomas Deimel   +6 more
wiley   +1 more source

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang   +12 more
wiley   +1 more source

Fully Automated Deep Learning-Based Pipeline for Evans Index Measurement from Raw 3D MRI. [PDF]

open access: yesNeurosci Inform
Barough SS   +6 more
europepmc   +1 more source

Loss, persistence and reversal of phenotypic traits

open access: yesBiological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni   +4 more
wiley   +1 more source

Sailing From Penalties to Accountability: Business Strategies and Governance for Firms to Innovate After Environmental Misconduct

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Firms' continuous pursuit of making a profit in the competitive market may ignore the actions related to environmental responsibilities. This set of actions for financial gains constitutes environmental misconduct, which not only harms ecosystems and communities but also brings reputational damage. Negative press and social media amplification
Ashutosh Singh   +3 more
wiley   +1 more source

The Application of Deep Learning Human Pose Estimation in Sport: A Systematic Review. [PDF]

open access: yesSports Med Open
Aulton C   +4 more
europepmc   +1 more source

Deep learning to predict future cognitive decline: a multimodal approach using brain MRI and clinical data. [PDF]

open access: yesFront Neuroimaging
Chattopadhyay T   +10 more
europepmc   +1 more source

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