Results 71 to 80 of about 78,969 (302)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Sensitivity analysis of a single phase to ground fault system in connection with high impedance faults: A case study

Cogent Engineering, 2020
Most of High-impedance faults (HIFs) occur due to broken conductors falling on high-resistivity desert soil in United Arab Emirates remain undetected due to incredibly low fault currents and endanger lives. A reliable detection method is needed.
Perumal Velmurugan, Adhir Baran Chattopadhayay   +1 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A Unified Method for Online Detection of Phase Variables and Symmetrical Components of Unbalanced Three-Phase Systems with Harmonic Distortion

Energies, 2019
This paper presents a method for online detection of symmetrical components of arbitrarily distorted and biased three-phase input signals. This method is based on Second-Order Generalized Integrators (SOGIs), for which a new tuning based on a gradient ...
Christoph M. Hackl, Markus Landerer
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Analysis of symmetrical components of harmonics for three phase power systems

, 1986
Includes bibliographical references.Harmonic distortion of three phase power systems is caused by large amounts of electric power consumers using power electronic installations (e.g. drives and rectifiers). It has a number of undesirable consequences and
Shum, Kwan Leung
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Understanding symmetrical components for power system modeling

, 2017
This book utilizes symmetrical components for analyzing unbalanced three-phase electrical systems, by applying single-phase analysis tools. The author covers two approaches for studying symmetrical components; the physical approach, avoiding many ...
Das, J C
core  

Estimation of symmetrical components and their orthogonal components under unknown frequencies and unknown biases

, 2017
An algorithm to estimate symmetrical components, orthogonal components and amplitudes of each sinusoidal component in three-phase power system signal under unknown frequencies and unknown biases is presented.
Rui Zhang, Hua Li, Zhaobi Chu, Bo Chen
core   +1 more source

On-line determination of Symmetrical Components by Sampling

, 2008
Symmetrical components of currents and voltages are used for the performance analysis of three-phase power systems (positive-sequence component) and for protection.
Lobos, T, Eichhorn, K F
core   +1 more source