Results 81 to 90 of about 357,530 (342)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

NASTRAN cyclic symmetry capability [PDF]

, 1973
A development for NASTRAN which facilitates the analysis of structures made up of identical segments symmetrically arranged with respect to an axis is described.
Harder, R. L., Macneal, R. H., Mason, J. B.   +2 more
core   +1 more source

Multiphase induction motor drives - a technology status review [PDF]

, 2007
The area of multiphase variable-speed motor drives in general and multiphase induction motor drives in particular has experienced a substantial growth since the beginning of this century.
Abbas, Abolhassani, Andrese, Apsley, Atkinson, Bakhshai, Benatmane, Bendixen, Bojoi, Bojoi, Bojoi, Bojoi, Bojoi, Bojoi, Bojoi, Bojoi, Casadei, Coates, Correa, Correa, Corzine, de Silva, Dente, Duran, E. Levi, Edelson, F. Profumo, Farina, Ferraris, Ferreira, Figureoa, Gataric, Gerada, Golubev, Golubev, Golubev, Gopakumar, Gopakumar, Gritter, H.A. Toliyat, Hadiouche, Hadiouche, Hodge, Hou, Iqbal, Iqbal, Iqbal, Iqbal, Iqbal, Jacobina, Jacobina, Jacobina, Jacobina, Jahns, Jones, Jones, Jones, Jones, Jouanne, Kelly, Kestelyn, Kestelyn, Kestelyn, Kianinezhad, Klingshirn, Levi, Levi, Levi, Levi, Lipo, Locment, Lu, Lyra, Mantero, Mantero, McCoy, Mecrow, Merabtene, Miller, Miranda, Mitcham, Mohapatra, Mohapatra, Mokhtari, Monti, Nelson, Ojo, Oriti, Oudjebour, Parsa, Pereira, Pereira, R. Bojoi, Razik, Ryu, Ryu, S. Williamson, Semail, Semail, Shi, Siala, Silva, Singh, Smith, Smith, Steiner, Sudhoff, Takami, Terrien, Toliyat, Toliyat, Toliyat, Toliyat, Toliyat, Ward, Weh, Williamson, Xu, Xu, Zhao, Zhao, Zheng   +121 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

The Performance of a Three-Phase Induction Motor under and over Unbalance Voltage

Tikrit Journal of Engineering Sciences, 2022
Voltage unbalance is an adverse global phenomenon impacting three-phase induction motor output. Three-phase source voltage may become imbalanced in a variety of respects, while a balanced system preserves stable voltage magnitude and angles in three ...
Abdulsatar H. Jassim, Arkan A. Hussein, Laith F. Abbas   +2 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Unity and Plurality of the European Cycle [PDF]

We apply uni- and multivariate unobserved components models to the study of European growth cycles. The multivariate dimension enables to search similar or, more strongly, common components among national GDP series (quarterly data from 1960 to 1999 ...
Guilhem Bentoglio, Jacky Fayolle, Matthieu Lemoine   +2 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source