Results 11 to 20 of about 748 (86)
Regulation of PHOX2B gene expression by the long non-coding natural antisense RNA PHOX2B-AS1. [PDF]
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Di Lascio S +12 more
europepmc +2 more sources
Comparison of Dysautonomia Across Species: Current Knowledge and Future Research Opportunities. [PDF]
ABSTRACT Primary dysautonomia is a complex and often fatal autonomic nervous system disease. This literature review consolidates information on dysautonomia across species. Electronic databases (PubMed, Google Scholar and the Equine Grass Sickness Fund website) were systematically searched for veterinary and human medical literature on the topic.
Atkins CN, Hahn CN, McGorum BC.
europepmc +2 more sources
A case report of Parry-Romberg syndrome. [PDF]
Changes made through two fat injection surgeries. Key Clinical Message Parry–Romberg syndrome is characterized by progressive dystrophy in one half of the face, which usually begins in childhood. Correct and timely diagnosis of this disease, as well as a multidisciplinary approach and timely surgical treatment to minimize the psychological effects and ...
Babaei K +3 more
europepmc +2 more sources
Alternative Splicing and CaV-Associated Channelopathies. [PDF]
Voltage‐gated calcium channels control vital cellular processes through complex alternative splicing mechanisms, and their dysfunction contributes to neurological, cardiac, endocrine, oncogenic, and muscular disorders. Recent discoveries of splicing‐related channelopathies have opened promising therapeutic pathways that target specific exons ...
Munyao W +7 more
europepmc +2 more sources
Crosstalk between Bone and Nerves within Bone
Some clues are given during biological processes as well as pathological disorders to allow the detection of the communication between bone and nerves within bone. The pattern of strings on the hand created by nature are intriguing and waiting for the wise play.
Qian‐Qian Wan +9 more
wiley +1 more source
Background. Chronic neuropathic pain is a condition affecting an increasing proportion of the general population and its management requires a comprehensive, multidisciplinary program. A growing body of evidence supports the use of hyperbaric oxygen therapy (HBOT) in several chronic neuropathic pain conditions; however, its role and efficacy remain ...
Simone Schiavo +6 more
wiley +1 more source
ABSTRACT Introduction Chronic pain affects 1 in 5 adults and children globally; however, management remains highly variable and low value care is common. Inconsistent recommendations among clinical practice guidelines for management of chronic pain contribute to suboptimal patient management.
Andrea J. Darzi +48 more
wiley +1 more source
Abstract This Scientific Opinion provides an assessment of beef cattle welfare focusing on risks related to flooring, water access, nutrition and feeding, high environmental temperatures, lack of environmental enrichment, lack of outdoor access, minimum space allowance and mixing practices. In addition, risks related to pasture and feedlots, weaning of
EFSA Panel on Animal Health and Welfare (AHAW) +27 more
wiley +1 more source
Engineering Innervated Musculoskeletal Tissues for Regenerative Orthopedics and Disease Modeling
Coupling of the peripheral nervous system to the musculoskeletal system and its implications on tissue engineering strategies for MSK regeneration and disease modeling. Abstract Musculoskeletal (MSK) disorders significantly burden patients and society, resulting in high healthcare costs and productivity loss.
Zhilong Zhou +5 more
wiley +1 more source

