Influence of facial cooling on carotid body tonic activity and sensitivity
Abstract Facial cooling can increase ventilation and augment the hypoxic ventilatory response. Whole body cooling increases both carotid body tonic activity and sensitivity; however, whether isolated facial cooling induces similar carotid body hyperexcitability was unknown.
Robyn Morley +5 more
wiley +1 more source
Single Potential Analysis of Cavernous Electric Activity in Spinal Cord Injury Patients [PDF]
Höppner, C. +3 more
core
Non-invasive imaging of sympathetic innervation of the pancreas in individuals with type 2 diabetes. [PDF]
Vyakaranam AR +6 more
europepmc +1 more source
The efficacy and physiological bases of small muscle mass exercise in health and disease
Abstract The conventional approach to aerobic exercise prescription involves large muscle mass exercise and the manipulation of variables such as training intensity, duration and frequency to promote desired adaptations. However, during whole‐body exercise, central limitations (i.e., neural, pulmonary and/or cardiac) constrain exercise tolerance and ...
Callum G. Brownstein
wiley +1 more source
Cerebrovascular regulation during heat stress
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley +1 more source
Brain strain: Blood flow and metabolism in environmental extremes
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak +3 more
wiley +1 more source
Differential responses to UCP1 ablation in classical brown versus beige fat, despite a parallel increase in sympathetic innervation. [PDF]
Naren Q +4 more
europepmc +1 more source
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts +13 more
wiley +1 more source
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand +2 more
wiley +1 more source
Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of Oxytocin (OT)-elicited reductions of body weight gain and adiposity in male diet-induced obese rats. [PDF]
Edwards MM +20 more
europepmc +1 more source

