Results 71 to 80 of about 53,521 (302)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Cardiac risk in recovered Covid-19 patients evaluated by 123I-mIBG

Scientific Reports
To determine whether cardiac sympathetic nervous dysfunction is present, in this single center prospective, non-randomized trial non-invasive SPECT/CT imaging using the radiotracer 123I-metaiodobenzylguanidine was performed in 33 recovered COVID-19 ...
Alessandro Liebich, Gabriel Sheikh, Ralph. A. Bundschuh, Malte Kircher, Alexander Dierks, Bernd Nittbaur, Philip Raake, Maximilian Rieger, Takahiro Higuchi, Christian H. Pfob, Constantin Lapa   +10 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

The Neuroanatomic Basis of the Acupuncture Principal Meridians [PDF]

, 2009
Acupuncture involves treating illness by inserting needles at specified body locations (acupoints). The Principal meridians are pathways that join acupoints with related physiologic effects.
Peter Dorsher
core   +1 more source

Extrinsic intestinal denervation modulates tumor development in the small intestine of ApcMin/+ mice [PDF]

, 2015
Background Innervation interacts with enteric immune responses. Chronic intestinal inflammation is associated with increased risk of colorectal cancer. We aimed to study potential extrinsic neuronal modulation of intestinal tumor development in a mouse ...
Benhaqi, Petra, Dietrich, Alexandra, Kasparek, Michael S., Kreis, Martin E., Liu, Verena, Schemann, Michael, Schneider, Marlon R., Seeliger, Hendrik   +7 more
core   +2 more sources

Sympathetic innervation in the larynx of cats.

Nippon Jibiinkoka Gakkai Kaiho, 1989
The site of origins, peripheral courses and intramucosal distribution of the sympathetic post-ganglionic nerve fibers supplying to the larynx were investigated by means of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) and Falck-Hillarp method in 51 cats.
openaire   +3 more sources

‘Where are the adults?’: Troubling child‐activism and children's political participation

British Educational Research Journal, EarlyView.
Abstract Children's political participation is a well‐established theme in childhood studies. In this article we offer an original account of child activism that takes into account the entangled and emergent aspect of children as activists. We begin with a historical and a conceptual review, noting the importance of mid‐20th century developments such ...
Sharon Hunter, Claire Cassidy
wiley   +1 more source

Sympathetic Renal Innervation and Resistant Hypertension

International Journal of Hypertension, 2011
Hypertension in chronic renal disease and renovascular disease is often resistant to therapy. Understanding the pathogenic mechanisms responsible for hypertension in these conditions may lead to improved and more targeted therapeutic interventions ...
Vito M. Campese, Elaine Ku, Jeanie Park
doaj   +1 more source

Long‐term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice

Journal of Cachexia, Sarcopenia and Muscle, 2021
Background The discovery of adrenoceptors, which mediate the effects of the sympathetic nervous system neurotransmitter norepinephrine on specific tissues, sparked the development of sympathomimetics that have profound influence on skeletal muscle mass ...
Anna Carolina Zaia Rodrigues, María Laura Messi, Zhong‐Min Wang, Henry Jacob Bonilla, Willard M. Freeman, Osvaldo Delbono   +5 more
doaj   +1 more source

Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]

, 2007
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma, Kennedy, Charles, Tasker, Paul N., Westfall, Timothy D.   +3 more
core   +1 more source