Results 91 to 100 of about 17,426,796 (291)

THE PARTICIPATION OF CATECHOLAMINES IN THE PATHOGENESIS OF DIABETIC CARDIOMYOPATHY

open access: yesМедицина в Кузбассе, 2020
Under normal conditions, the sympathetic nervous system, through its main mediators (catecholamines) plays an important role in the functioning of the cardiovascular system.
Алексей Михайлович Чаулин   +2 more
doaj  

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

open access: yesAnimal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang   +6 more
wiley   +1 more source

Restoration of gamma-aminobutyric acid homeostasis: A novel approach to alleviating central nervous system injury–associated immunodepression syndrome

open access: yesNeural Regeneration Research
Injuries to the central nervous system can disrupt body functions and often cause excessive sympathetic activity, leading to immune suppression known as central nervous system injury–associated immunodepression syndrome.
Ping Yang   +3 more
doaj   +1 more source

Drugs and the autonomic nervous system [PDF]

open access: yes, 2012
The nervous systems can initially be divided up into the central and peripheral nervous systems. The central nervous system is the brain and spinal cord and drugs that modify the central nervous system are considered as a subject in systematic ...
Doggrell, Sheila
core  

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

open access: yesArthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat   +14 more
wiley   +1 more source

Sympathetic signals beneath the surface: fresh insights from skin and muscle

open access: yesFrontiers in Neuroscience
The sympathetic branch of the autonomic nervous system, known for its governance of the “fight or flight” response, has attracted newfound interest due to its role in maintaining bodily homeostasis in various tissue types.
Tina Tian, Patricia Jillian Ward
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Guideline for the application of heart rate and heart rate variability in occupational medicine and occupational health science

open access: yesJournal of Occupational Medicine and Toxicology
This updated guideline replaces the “Guideline for the application of heart rate and heart rate variability in occupational medicine and occupational health science” first published in 2014.
Stefan Sammito   +5 more
doaj   +1 more source

Acute effects of THC and a CBD+THC combination on cardiovascular haemodynamics and respiratory muscle activity during loaded breathing in healthy adults: A randomized placebo‐controlled crossover study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the acute effects of cannabidiol plus tetrahydrocannabinol (CBD+THC) and tetrahydrocannabinol (THC) oils on cardiovascular haemodynamics, respiratory muscle activity and peripheral tissue perfusion in healthy adults. Methods In this randomized, double‐blind, crossover trial, participants received orally administered ...
Edna Karla Ferreira Laurentino   +9 more
wiley   +1 more source

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