Results 81 to 90 of about 318,050 (321)

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Вплив фізичних навантажень на організм студентів з переважанням симпатичної нервової системи [PDF]

, 2003
Influence of physical loadings on man' organism with prevalence of sympathetic nervous system studied in the research. Antropometric and functional data have established with the questionnaires about influence of physical exercises and development of ...
Довгань, О.М.
core  

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Local sympathetic nerve depletion does not alter vitiligo progression in a mouse model

Frontiers in Medicine
Vitiligo, an autoimmune skin disorder characterized by melanocyte loss, has long been associated with sympathetic nervous system activity. Clinical observations have suggested links between psychological stress, sympathetic activation, and vitiligo ...
Zhichao Hu, Zhichao Hu, Ting Chen, Ting Chen, Ting Chen, Daoming Chen   +5 more
doaj   +1 more source

Sartorial symbols of social class elicit class-consistent behavioral and physiological responses: a dyadic approach. [PDF]

, 2014
Social rank in human and nonhuman animals is signaled by a variety of behaviors and phenotypes. In this research, we examined whether a sartorial manipulation of social class would engender class-consistent behavior and physiology during dyadic ...
Kraus, Michael W, Mendes, Wendy Berry
core   +2 more sources

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

18F‐Radiopharmaceutical Diversification Enabled by Deaminative Cross‐Electrophile Couplings

Angewandte Chemie, EarlyView.
A general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Isabella F. Ogilvy, Joseph Ford, Sebastiano Ortalli, Evelien Renders, Thomas R. Hayes, Shuanglong Liu, Inne Mortiers, Anastasia Nikolopoulou, Alexandre M. Sorlin, Andrés A. Trabanco, Matthew Tredwell, Peter J. J. A. Buijnsters, Rhys Salter, Véronique Gouverneur   +13 more
wiley   +2 more sources

The Effect of the Vestibular System on Bone Regeneration: a Look at the Vestibular ‎System Beyond its Classical Role [PDF]

Journal of Paramedical Science and Rehabilitation
Purpose: The purpose of this study is to investigate the effect of the vestibular system on the bone formation process and the possible path of this effect.
S khakzand, Y Lotfi, M Shabani
doaj   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

Advanced Science, EarlyView.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu, Wenpin Qin, Jialu Gao, Yihan Guo, Xiaoxiao Han, Zhangyu Ma, Xiaokang Zhang, Jie He, Jing Liu, Bo Gao, Changjun Li, Lina Niu, Jianfei Yan, Kai Jiao   +13 more
wiley   +1 more source