Results 21 to 30 of about 3,622 (118)

Bilateral exudative retinal detachments after subretinal gene therapy with voretigene neparvovec-rzyl for RPE65 Leber Congenital Amaurosis

open access: yesAmerican Journal of Ophthalmology Case Reports, 2023
Purpose: To report panuveitis with exudative retinal detachments in a healthy 27-year-old woman with biallelic mutations in the RPE65 gene, who underwent bilateral sequential gene therapy with subretinal administration of voretigene neparvovec-rzyl ...
Alcina K. Lidder   +6 more
doaj   +1 more source

Roles of non‐coding RNAs in eye development and diseases

open access: yesWIREs RNA, Volume 14, Issue 5, September/October 2023., 2023
ncRNAs participate in different ocular diseases and eye development. Abstract The prevalence of ocular disorders is dramatically increasing worldwide, especially those that cause visual impairment and permanent loss of vision, including cataract, glaucoma, age‐related macular degeneration, and diabetic retinopathy.
Xinrui Shi   +6 more
wiley   +1 more source

Azathioprine‐induced vanishing bile duct syndrome: The value of early thiopurine metabolism assessment

open access: yesBritish Journal of Clinical Pharmacology, Volume 89, Issue 8, Page 2625-2630, August 2023., 2023
About 15% to 28% of patients treated with thiopurines experienced adverse drug reactions, such as haematological and hepatic toxicities. Some of these related to the polymorphic activity of the thiopurine S‐methyltransferase (TPMT), the key detoxifying enzyme of thiopurine metabolism.
Laurent Chouchana   +5 more
wiley   +1 more source

Clinical and medico‐legal considerations in endodontics

open access: yesAustralian Dental Journal, Volume 68, Issue S1, Page S153-S164, June 2023., 2023
Abstract Endodontic treatment can be challenging for a number of reasons, including the microscopic nature of the clinical environment, reliance on tactile sensation and lack of direct visualization of the work being performed. Commonly, endodontic patients present with pain and distress, which can exacerbate an already difficult clinical situation ...
M Johnstone, M Evans
wiley   +1 more source

Clinical Features of Sympathetic Ophthalmia in a Tertiary Referral Center in Thailand

open access: yesSiriraj Medical Journal, 2017
Background: Sympathetic ophthalmia is a rare bilateral granulomatous intraocular inflammation, developed after ocular injury in one eye. If untreated, there is a potential risk of developing visual impairment in both eyes.
Sutasinee Boonsopon   +4 more
doaj   +3 more sources

Vogt–Koyanagi–Harada syndrome in the setting of COVID‐19 infection

open access: yesClinical Case Reports, Volume 11, Issue 3, March 2023., 2023
Abstract To report a case of Vogt–Koyanagi–Harada disease (VKH) in a 27‐year‐old male 2 weeks proceeding COVID‐19 infection onset. Severe complications of VKH can be avoided by early diagnosis and adequate treatment with corticosteroids and immunosuppressants. It is possible that COVID‐19 was a potential immunological trigger of VKH in our patient.
Tiffany Eatz, Jude Hassan Charles
wiley   +1 more source

Cyclophotocoagulation in Neovascular Glaucoma with Near‐Total Synechial Angle Closure

open access: yesCase Reports in Ophthalmological Medicine, Volume 2023, Issue 1, 2023., 2023
Objective. To describe a single surgeon’s experience utilizing prompt primary slow‐burn transscleral cyclophotocoagulation (CPC) with prior or concurrent anti‐VEGF and subsequent aqueous shunt as needed in NVG eyes with near‐total synechial angle closure at presentation. Methods.
Jessie Wang   +3 more
wiley   +1 more source

Phacoanaphylactic endophthalmitis as sympathetic ophthalmia after corneoscleral injury

open access: yesРоссийский офтальмологический журнал, 2021
A penetrating corneoscleral injury case with the development of bilateral phacoanaphylactic inflammation of a sympathetic ophthalmia kind in a 59-year-old woman is described.
N. L. Leparskaya   +2 more
doaj   +1 more source

Guideline for the treatment of no light perception eyes induced by mechanical ocular trauma

open access: yesJournal of Evidence-Based Medicine, Volume 15, Issue 3, Page 302-314, September 2022., 2022
Abstract Severe mechanical ocular trauma with no light perception (NLP) predicts a poor prognosis of visual acuity and enucleation of the eyeball. Since the innovative treatment concept of exploratory vitreoretinal surgery has developed and treatment technology has advanced, the outcomes of severe ocular trauma treatment in NLP patients have greatly ...
Hua Yan   +59 more
wiley   +1 more source

MicroPulse Transscleral Laser Therapy Demonstrates Similar Efficacy with a Superior and More Favorable Safety Profile Compared to Continuous‐Wave Transscleral Cyclophotocoagulation

open access: yesJournal of Ophthalmology, Volume 2022, Issue 1, 2022., 2022
Purpose. The aim of this study was to compare effectiveness and safety of MicroPulse transscleral laser therapy (MP‐TLT) using the original MicroPulse P3® device and continuous‐wave transscleral cyclophotocoagulation (CW‐TSCPC) using the G‐Probe® device in glaucoma. Methods. Spherical equivalent, intraocular pressure (IOP), best‐corrected visual acuity
Enrico Bernardi   +2 more
wiley   +1 more source

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