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Acta Psychiatrica Scandinavica, 1953 Postoperative Pharmacokinetics and Sympatholytic Effects of Dexmedetomidine
Anesthesia & Analgesia, 1997Dexmedetomidine is a selective alpha2-adrenoceptor agonist with centrally mediated sympatholytic, sedative, and analgesic effects. This study evaluated: 1) pharmacokinetics of dexmedetomidine in plasma and cerebrospinal fluid (CSF) in surgical patients; 2) precision of a computer-controlled infusion protocol (CCIP) for dexmedetomidine during the ...
P, Talke +3 more
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Sympatholytic interventions and vascular remodelling.
Basic research in cardiology, 1991Most of the results on the effects of sympatholytic agents on vascular remodelling came from studies involving hypertensive animals. Therefore, it is often difficult to dissociate the antihypertensive property of the drugs from those caused by the direct action of the drugs on the structure of the blood vessels. However, some general conclusions can be
R M, Lee, D J, Gzik
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7-(Trifluoromethyl)-4-aminoquinoline hypotensives: novel peripheral sympatholytics
Journal of Medicinal Chemistry, 1986J M McCall, John M McCall
exaly