Results 121 to 130 of about 3,502 (242)

L-Type Ca_v1.3 and HCN Channels Mediate Heart Rate Acceleration by Catecholamines. [PDF]

Circ Res
Torre E, Faure M, Bidaud I, Baudot M, Gaillardon M, Pereira de Vasconcelos W, Laarioui S, Talssi L, Engeland B, Reiken S, Saponaro A, Chen BX, Moroni A, D'Souza A, Isbrandt D, Marks AR, Marx SO, Mesirca P, Mangoni ME.   +18 more
europepmc   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

Maternal Primary Sjögren's Syndrome Complicated by Irreversible Fetal Third-Degree Congenital Heart Block: A Case Report From Nepal. [PDF]

Clin Case Rep
Shah P, Jaiswal P, Adhikari P, Jaiswal SK, Parajuli K.   +4 more
europepmc   +1 more source

Effect of Intramuscular Adrenaline on Histamine‐Induced Hypotension: A Randomised Placebo‐Controlled Pilot Trial

Allergy, EarlyView.
Histamine infusions induce reproducible severe hypotension. Intramuscular adrenaline showed ‘supposedly therapeutic’ plasma concentrations but did not produce a sustained clinically relevant improvement in shock in the majority of recipients. These findings question adrenaline pharmacokinetic surrogate thresholds and support the need for faster and ...
Matthias Weiss‐Tessbach, Al Medina Dizdarevic, Thorsten Bischof, Christa Firbas, Alexander Taschner, Eva‐Luise Ritter‐Hobl, Barbara Steinlechner, Eva Fischer, Lorenz Sonnberger, Georg Gelbenegger, Jolanta M. Siller‐Matula, Christian Schoergenhofer, Bernd Jilma   +12 more
wiley   +1 more source

Persistence with medical glaucoma therapy in newly diagnosed patients. [PDF]

Med Hypothesis Discov Innov Ophthalmol
Menino J, Camacho P, Coelho A.
europepmc   +1 more source

Efficacy and safety of different vasopressor infusions on feto‐maternal outcomes in normotensive patients undergoing caesarean delivery: a systematic review and network meta‐analysis of randomised controlled trials

Anaesthesia, EarlyView.
Summary Introduction Phenylephrine infusion is widely endorsed by guidelines as the preferred prophylactic drug for spinal hypotension in patients undergoing caesarean delivery; however, clinical practice continues to show marked variability in the selection of vasopressor drugs.
Narinder Pal Singh, Jeetinder Kaur Makkar, Bisman Jeet Kaur Khurana, Anuradha Borle, Preet Mohinder Singh   +4 more
wiley   +1 more source

Working group summary of the 2023 full update of the Finnish national guidelines for paediatric lower respiratory tract infections. [PDF]

Acta Paediatr
Backman K, Helminen M, Kekäläinen E, Mikkola I, Nieminen T, Nuolivirta K, Peltola V, Seuri R, Walle SM, Ruuska-Loewald T.   +9 more
europepmc   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Part II - imidazolines and rhinitis medicamentosa: how can we tackle the rebound dilemma? [PDF]

Front Pharmacol
Stinson RJ, Sadofsky LR.
europepmc   +1 more source

Imaging of the equine abdomen using point of care ultrasound (POCUS): Effects of sedation on intestinal motility in horses

Australian Veterinary Journal, EarlyView.
Background Point of care ultrasonographic (POCUS) assessment of the equine abdomen is now readily available to the equine practitioner using hand‐held ultrasound transducers. Commonly used medications may alter the sonographic appearance or function of the small intestine, caecum or colon.
F Freccero, B Padalino, A Carstens, SL Raidal   +3 more
wiley   +1 more source