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Identification of Sympathomimetic Amines as Tetraphenylborates

Journal of Pharmaceutical Sciences, 1963
The tetraphenylborate salts of sympathomimetic amines are readily isolated in a highly pure state even from low concentrations in complex mixtures. Therefore, melting points, infrared, and ultraviolet spectral characteristics of these salts were studied as an aid to the identification of the medicinally important sympathomimetic amines.
Joseph E. Sinsheimer, Edward Smith
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Adrenergic (Sympathomimetic) Drugs

2006
Adrenaline is a hormone produced within the adrenal gland in response to stress that increases heart rate, strengthens the force of the heart’s contraction and cardiac output, increases blood pressure and opens up the bronchioles in the lungs, and raises the blood levels of glucose and lipids among other effects.
Ruben Vardanyan, Victor J. Hruby
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The Mechanism of Some Sympathomimetic Amines

Pharmacology, 1973
The relative increase of heart work caused by aminorex in dogs is greater in the right ventricle than in the left. In contrast, noradrenalin, amphetamine, ephedrine and tyramine are more effective in the left ventricle. In contrast to sympathomimetics, aminorex increased the pulmonary vascular resistance more than the total peripheral resistance.
J. Schuster, Margarita Ihli
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Uropharmacology: VIII. Sympathomimetic agents

Urology, 1978
Sympathomimetic drugs stimulate the receptors of the sympathetic nervous system. Although the bladder possesses sympathetic receptors, sympathomimetic drugs, in general, have little effect on bladder function. Their most useful clinical applications on the urinary tract are to increase or decrease bladder resistance.
Larry T. Welch   +2 more
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Sympathomimetic vs Non-Sympathomimetic Drugs in the Treatment of Heart Failure

1989
The syndrome of congestive heart failure is characterized by a reduced stroke volume and peripheral circulatory changes that redistribute blood flow to metabolically active tissues. Conventional inotropic therapy has been limited by the moderate potency and marked toxicity of the glycosides [1] and the ob ligate i.v.
G. Baumann, S. B. Felix
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Identification of Some Sympathomimetic Amines*

Journal of the American Pharmaceutical Association (Scientific ed.), 1955
Abstract Phenylthioureas, benzamides, benzenesulfonamides, 3,5‐dinitrobenzoates, and 2,4‐dinitrobenzoates of ten commonly used sympathomimetic amines were prepared and when possible the products crystallized and proved by analysis. Melting points of the pure, crystalline derivatives serve as a means of identification.
William H Fischer, Elmer M. Plein
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Sympathomimetic Agents in the Treatment of Shock

Annals of Internal Medicine, 1974
Abstract Sympathomimetic drugs can be very useful in the treatment of shock but only when used as part of an overall therapeutic plan to improve tissue perfusion and deal with the pathophysiologica...
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Amphetamines/Sympathomimetic Amines

2020
Amphetamines and sympathomimetic amines mimic the actions of the endogenous neurotransmitters that stimulate the sympathetic nervous system. Amphetamine and methamphetamine are used therapeutically to treat narcolepsy, attention-deficit disorder, and obesity.
Michele M. Crosby, Karla A. Moore
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Sympathomimetic effects of pindolol in depression

Trends in Pharmacological Sciences, 2001
In a recent TiPS Opinion article, Artigas et al1xHow does pindolol improve antidepressant action?. Artigas, F. et al. Trends Pharmacol Sci. 2001; 22: 224–228Abstract | Full Text | Full Text PDF | PubMed | Scopus (141)See all References1. reviewed, on the basis of animal and human studies, the mechanisms that might underlie the beneficial (acceleration ...
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Classification of Sympathomimetic Amines

1972
Long before the mechanism of action of the indirectly acting sympathomimetic amines was understood, it was clear that the amines of this group differ pharmacologically. For instance, while cocaine potentiates the effects of adrenaline (FroHlich and Loewi, 1910) it antagonizes the effects of tyramine (Tainter and Chang, 1927).
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