Results 201 to 210 of about 4,147 (297)

Intraoperative Analgesic Requirements in Dogs Receiving Retromammillary or Erector Spinae Plane Blocks for Thoracolumbar or Lumbar Hemilaminectomy: A Single-Center Retrospective Cohort Study. [PDF]

Vet Sci
Cavalcanti-McKenzie M, Moura RA, Vettorato E, Romano M, Chiavaccini L, De Gennaro C, Maxwell EA, Otero PE, Portela DA.   +8 more
europepmc   +1 more source

Aquablation as salvage therapy for benign prostatic hyperplasia: an international multicentre study

BJU International, EarlyView.
Objective Our objective was to evaluate the safety and effectiveness of Aquablation® as a salvage therapy in patients who underwent prior intervention for benign prostatic hyperplasia (BPH). Materials and Methods We retrospectively analysed 1887 consecutive men from the International Collaborative Aquablation Research Urology Society database between ...
Anouk Leathead, Nick Lee, Adel Arezki, David Bouhadana, Liam Murad, Tarek Benzouak, Iman Sadri, Rosie Foucault, Aalya Hamouda, Jeffrey Sioufi, Ilan Ohana, Joshua Cabral, Margaret Gannon, Gregory Raster, David Nusbaum, Abdulla Alameeri, John Klein, Inderjit Singh, James Kearns, Shawn Marhamati, Alexander Glaser, Brian Helfand, Dean Elterman, Tiago Rodrigues, Kevin C. Zorn   +24 more
wiley   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

Influenza A-Induced Myocarditis and Persistent Complete Heart Block in Pregnancy. [PDF]

Cureus
Othman Z, Catton H, Mann T, Dwyer B, Missouris CG, Mandal AKJ.   +5 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Transient Bilateral Fixed Dilated Pupils Following Papaverine Use During Intracranial Microvascular Decompression: A Case Report. [PDF]

Cureus
Idayathulla S, Nawaz S, Shaikh N, Nainthramveetil M, Ma R, Gonzalez FR.   +5 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Ophthalmology in the Ebers Papyrus: a translation-based reassessment of ancient Egyptian eye remedies. [PDF]

Eye (Lond)
Maskill D.
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Phenylephrine Vs. Norepinephrine on the Renin-Angiotensin-Aldosterone System and Postoperative Complications in Acute Abdomen Emergency Surgery: A Randomized Controlled Trial. [PDF]

Crit Care Med
Chen J, Wang X, Yin T, Guo J, Chen X, Chen Y, Liu Y, Sun Z, Wang K, Zhang Y, Zhang Z, Shen L, Zhao L, Wu Y, Liu S.   +14 more
europepmc   +1 more source