Results 101 to 110 of about 47,169 (292)

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming   +14 more
wiley   +1 more source

Forging Just Climate Policies: Reconciling Justice Perceptions in Deliberative Mini‐Publics

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT Demands for ambitious climate measures have been accompanied by calls for a just transition, implying policies that take into account aspects of social justice in climate change mitigation. In many countries, deliberative mini‐publics, such as Citizens' Assemblies and Citizens' Juries, have been convened to develop recommendations for socially
Katariina Kulha
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Terms of consolation

open access: yesКонсультативная психология и психотерапия, 2009
In the article different terms of consolation are reviewed (don’t give up! everything will be ok, that’s ok etc). Author assumes that new methodology, which combines linguistic and psychological analyses may expand academic views on coping and sympathy ...
Fedunina N.Y.
doaj  

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Interwoven Threads: Sympathetic Knowledge in George Eliot and Spinoza

open access: yesJournal of Spinoza Studies
Before achieving success as a novelist, George Eliot spent several years translating Spinoza’s Ethics. Previous scholarship on Spinoza and Eliot has generally assumed that Eliot’s novels are wholly influenced by Spinoza, or that they can even be read as ‘
Dan Taylor
doaj   +1 more source

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