Irritable bowel syndrome (IBS), a chronic disorder, greatly impacts the lives of those affected. Approximately one quarter of the North American population suffers from this condition that includes abdominal pain, discomfort and alterations in normal ...
Joyce K. Anastasi +4 more
doaj +1 more source
Angiotensin receptors and neuropathic pain
. Growing evidence implicates the renin–angiotensin system (RAS) in multiple facets of neuropathic pain (NP). This narrative review focuses primarily on the major bioactive RAS peptide, Angiotensin II (Ang II), and its receptors, namely type 1 (AT1R) and
Mihály Balogh +3 more
doaj +1 more source
The longitudinal interplay between negative and positive symptom trajectories in patients under antipsychotic treatment: a post hoc analysis of data from a randomized, 1-year pragmatic trial [PDF]
BACKGROUND: Schizophrenia is a highly heterogeneous disorder with positive and negative symptoms being characteristic manifestations of the disease. While these two symptom domains are usually construed as distinct and orthogonal, little is known about ...
Ascher-Svanum, H +6 more
core +2 more sources
A meta-analysis of the relation between therapeutic alliance and treatment outcome in eating disorders. [PDF]
The therapeutic alliance has demonstrated an association with favorable psychotherapeutic outcomes in the treatment of eating disorders (EDs). However, questions remain about the inter-relationships between early alliance, early symptom improvement, and ...
Antoniou +65 more
core +3 more sources
Somatic symptom disorder in dermatology [PDF]
Somatic symptom disorder (SSD) is defined by the prominence of somatic symptoms associated with abnormal thoughts, feelings, and behaviors related to the symptoms, resulting in significant distress and impairment.
Levenson, James L. +2 more
core +2 more sources
Although pain is the most feared symptomatic component of having cancer and being treated for it, cancer-related fatigue is the most severe and impairing symptom that cancer patients and cancer survivors face.
Xin Shelley Wang, Charles S Cleeland
doaj +1 more source
This paper argues that despite an appearance of rupture, journalism is in an era of good fortune. While it would be both premature and historically naive to point at a new golden era, there is reason to see a strengthening of journalism's sense of core responsibilities emerging from the challenges and opportunities which new technologies present.
Conboy, Martin, Eldridge, Scott A.
openaire +2 more sources
Harnessing the placebo effect to enhance emotion regulation effectiveness and choice
The placebo effect demonstrates how positive expectancies shape the effectiveness of various treatments. Across studies, placebo treatments are interventions (creams, pills, etc.) that are presented to individuals as, and are learned to be, beneficial ...
Roni Shafir, Maya Israel, Luana Colloca
doaj +1 more source
Are estimates of socioeconomic inequalities in chronic disease artefactually narrowed by self-reported measures of prevalence in low-income and middle-income countries? Findings from the WHO-SAGE survey [PDF]
Background: The use of self-reported measures of chronic disease may substantially underestimate prevalence in low-income and middle-income country settings, especially in groups with lower socioeconomic status (SES).
Aitsi-Selmi, A. +6 more
core +2 more sources
Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats
Background Production of inflammatory mediators by reactive microglial cells in the brain is generally considered the primary mechanism underlying the development of symptoms of sickness in response to systemic inflammation.
Elisabeth G. Vichaya +5 more
doaj +1 more source

