Results 11 to 20 of about 1,397,203 (301)

Pilot Testing of a Nurse-Led Basic Symptom Self-management Support for Patients Receiving First-Line Systemic Outpatient Anticancer Treatment: A Cluster-Randomized Study (Symptom Navi Pilot Study). [PDF]

open access: yes, 2021
BACKGROUND The Symptom Navi Program (SNP) is a nurse-led intervention supporting basic symptom self-management for patients with any cancer diagnosis. The SNP has been accepted by patients and healthcare professionals alike.
Borner, M.   +33 more
core   +3 more sources

Symptom-burden in people living with frailty and chronic kidney disease

open access: yes, 2020
BackgroundFrailty is independently associated with worse health-related quality of life (HRQOL) in chronic kidney disease (CKD). However, the relationship between frailty and symptom experience is not well described in people living with CKD.
HML Young (7711055)   +8 more
core   +5 more sources

Investigating the potential for expediting diagnosis of ovarian cancer via prompt symptom recognition & "targeted screening" [PDF]

open access: yes, 2009
PhDThis thesis explores the potential for using symptoms as a tool to bring forward the diagnosis of ovarian cancer. Current evidence supports the existence of prediagnostic symptoms, however symptom lead time has yet to be adequately quantified ...
Lim, Anita Wey Wey
core   +4 more sources

Perceived symptom manageability - synthesis of a new use of a known concept based on a sample of HIV outpatients [PDF]

open access: yes, 2012
Symptom management issues are regularly discussed in medical follow-up appointments, however, despite the integration of patients' perspectives in symptom management negotiations, traditional-ly used measures (i.e., symptom severity and frequency) to ...
Fierz, Katharina
core   +1 more source

Significance of Symptom Clustering in Palliative Care of Advanced Cancer Patients

open access: yes, 2011
Patients with advanced cancer often experience multiple concurrent symptoms. To explore this symptom clustering and its associated parameters , we prospectively surveyed 427 consecutive patients on admission to the Palliative Care Unit.
蔡兆勳;吳治勳;邱泰源;陳慶餘   +1 more
core   +2 more sources

Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats

open access: yesJournal of Neuroinflammation, 2020
Background Production of inflammatory mediators by reactive microglial cells in the brain is generally considered the primary mechanism underlying the development of symptoms of sickness in response to systemic inflammation.
Elisabeth G. Vichaya   +5 more
doaj   +1 more source

Tracking macrophages in diabetic neuropathy with two-color nanoemulsions for near-infrared fluorescent imaging and microscopy

open access: yesJournal of Neuroinflammation, 2021
Background The incidence of diabetes and diabetic peripheral neuropathy continues to rise, and studies have shown that macrophages play an important role in their pathogenesis.
James M. Nichols   +5 more
doaj   +1 more source

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment

open access: yesActa Neuropathologica Communications, 2018
Chemotherapy-induced cognitive impairment (CICI) is a commonly reported neurotoxic side effect of chemotherapy, occurring in up to 75% cancer patients. CICI manifests as decrements in working memory, executive functioning, attention, and processing speed,
Jiacheng Ma   +4 more
doaj   +1 more source

Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer

open access: yesActa Neuropathologica Communications, 2020
Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used chemotherapeutic, induces neuronal mitochondrial dysfunction in vivo and in vitro ...
Krystal English   +5 more
doaj   +1 more source

Harnessing the placebo effect to enhance emotion regulation effectiveness and choice

open access: yesScientific Reports, 2023
The placebo effect demonstrates how positive expectancies shape the effectiveness of various treatments. Across studies, placebo treatments are interventions (creams, pills, etc.) that are presented to individuals as, and are learned to be, beneficial ...
Roni Shafir, Maya Israel, Luana Colloca
doaj   +1 more source

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