Results 11 to 20 of about 1,253,107 (314)

Pilot Testing of a Nurse-Led Basic Symptom Self-management Support for Patients Receiving First-Line Systemic Outpatient Anticancer Treatment: A Cluster-Randomized Study (Symptom Navi Pilot Study). [PDF]

, 2021
BACKGROUND The Symptom Navi Program (SNP) is a nurse-led intervention supporting basic symptom self-management for patients with any cancer diagnosis. The SNP has been accepted by patients and healthcare professionals alike.
Borner, M., Stoffel, Barbara, Kuhn-Bächler, T., Zürcher-Florin, Sabin, Biber, R., Peters, Solange, Bana, Marika, Bütikofer, Lukas, Kropf-Staub, S., Biber, Rebecca, Kropf-Staub, Susanne, Malin, Diana, Eicher, Manuela, Cantoni, Nathan, Näf, Ernst, Ribi, Karin, Näf, E., Bütikofer, L., Eicher, M., Borner, Markus, Malin, D., Bana, M., Ribi, K., Blaeuer, Cornelia, Seeger, T., Kuhn-Bächler, Trudy, Peters, S., Betticher, Daniel, Blaeuer, C., Stoffel, B., Cantoni, N., Zürcher-Florin, S., Seeger, Thomas, Betticher, D.   +33 more
core   +1 more source

Perceived symptom manageability - synthesis of a new use of a known concept based on a sample of HIV outpatients [PDF]

, 2012
Symptom management issues are regularly discussed in medical follow-up appointments, however, despite the integration of patients' perspectives in symptom management negotiations, traditional-ly used measures (i.e., symptom severity and frequency) to ...
Fierz, Katharina
core   +1 more source

Significance of Symptom Clustering in Palliative Care of Advanced Cancer Patients

, 2011
Patients with advanced cancer often experience multiple concurrent symptoms. To explore this symptom clustering and its associated parameters , we prospectively surveyed 427 consecutive patients on admission to the Palliative Care Unit.
蔡兆勳;吳治勳;邱泰源;陳慶餘, TSAI, JAW-SHIUN;WU, CHIH-HSUN;CHIU, TAI-YUAN;CHEN, CHING-YU   +1 more
core   +2 more sources

SPECIAL ISSUE: THE 50th ANNIVERSARY OF THE NATIONAL CANCER ACT OF 1971 - REVIEW - CANCER-RELATED FATIGUE: WHAT WE HAVE LEARNED AND WHAT ARE THE CHALLENGES FOR THE FUTURE

Journal of Cancer Rehabilitation, 2021
Although pain is the most feared symptomatic component of having cancer and being treated for it, cancer-related fatigue is the most severe and impairing symptom that cancer patients and cancer survivors face.
Xin Shelley Wang, Charles S Cleeland
doaj   +1 more source

Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats

Journal of Neuroinflammation, 2020
Background Production of inflammatory mediators by reactive microglial cells in the brain is generally considered the primary mechanism underlying the development of symptoms of sickness in response to systemic inflammation.
Elisabeth G. Vichaya, Sajida Malik, Luba Sominsky, Bianca G. Ford, Sarah J. Spencer, Robert Dantzer   +5 more
doaj   +1 more source

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment

Acta Neuropathologica Communications, 2018
Chemotherapy-induced cognitive impairment (CICI) is a commonly reported neurotoxic side effect of chemotherapy, occurring in up to 75% cancer patients. CICI manifests as decrements in working memory, executive functioning, attention, and processing speed,
Jiacheng Ma, XiaoJiao Huo, Matthew B. Jarpe, Annemieke Kavelaars, Cobi J. Heijnen   +4 more
doaj   +1 more source

Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer

Acta Neuropathologica Communications, 2020
Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used chemotherapeutic, induces neuronal mitochondrial dysfunction in vivo and in vitro ...
Krystal English, Andrew Shepherd, Ndidi-Ese Uzor, Ronnie Trinh, Annemieke Kavelaars, Cobi J. Heijnen   +5 more
doaj   +1 more source

Tracking macrophages in diabetic neuropathy with two-color nanoemulsions for near-infrared fluorescent imaging and microscopy

Journal of Neuroinflammation, 2021
Background The incidence of diabetes and diabetic peripheral neuropathy continues to rise, and studies have shown that macrophages play an important role in their pathogenesis.
James M. Nichols, Caitlin V. Crelli, Lu Liu, Hoang Vu Pham, Jelena M. Janjic, Andrew J. Shepherd   +5 more
doaj   +1 more source

Autoimmune regulation of chronic pain

PAIN Reports, 2021
. Chronic pain is an unpleasant and debilitating condition that is often poorly managed by existing therapeutics. Reciprocal interactions between the nervous system and the immune system have been recognized as playing an essential role in the initiation
Michael J. Lacagnina, Cobi J. Heijnen, Linda R. Watkins, Peter M. Grace   +3 more
doaj   +1 more source

Respiratory distress symptom intervention for non-pharmacological management of the lung cancer breathlessness-cough-fatigue symptom cluster: randomised controlled trial

, 2022
Objectives In lung cancer, three prominent symptoms, such as breathlessness, cough and fatigue, are closely related with each other forming a ‘respiratory distress symptom cluster’.
Yorke, J., Khan, A., Molasiotis, A., Smith, J., Haines, J., Punnett, G., MacKereth, P., Johnson, M. J., Lloyd Williams, M., Ryder, D., Krishan, A., Blackhall, F., Davies, L.   +12 more
core   +1 more source